Source: International Congress 2016 – Best abstracts in physical activity and telemedicine
Disease area: Airway diseases

Abstract

INTRODUCTION: Physical Activity (PA) is an important factor to measure in patients with COPD (chronic obstructive pulmonary disease) because low PA is associated with poorer long-term outcomes. However, the optimum way to analyse and report PA data; or if PA is associated with other clinical characteristics, is unknown in COPD.METHOD: We explored PA within a secondary care COPD cohort (COPDMAP). Sensewear Armband PA monitors (SWM) were used to obtain readings over 7 days for 55 patients. Clinical characteristics including spirometry were also recorded.PA variables were used in a factor analysis to determine underlying patterns of activity within the cohort and verified in two further separate cohorts.RESULTS: PA variables were positively correlated with each other (p<0.05). Two underlying factors were found, these corresponded to:1. 'General Daily Activity', 'GDA' associated with the number of 2 min bouts of moderate activity in 24hr, factor loading (FL) =0.94.2. 'Purposeful Physical Activity', 'PPA' associated with number of 20 min bouts of moderate activity per 24 hours, FL=0.84.

Clinical correlates of 2 minute bouts and 20 minute bouts per 24hrs

	2 minute bouts		20 minute bouts
Variable	r	p-value	r	p-value
Post Bronchodilator Forced Expiratory Volume (FEV1)	0.34	0.001	0.47	0.001
Inspiratory Capacity (IC)	0.35	0.017	0.41	0.004
Post Bronchodilator Forced Volume Capacity (FVC)	0.26	0.082	0.47	0.001
6 Minute Walk Test (6MWT)	0.60	<0.001	0.46	<0.001
Hb levels in blood	0.01	0.928	0.31	0.036

 

CONCLUSIONS:We have found two distinct types of activity within a secondary care COPD cohort; that of 'General Daily Activity' 'GDA' and 'Purposeful Physical Activity', 'PPA'. These have distinct clinical associates.


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Chris Newby (Leicester, United Kingdom), Chris Newby, Karam Aboud, Bethan Barker, Maria Shelley, Karen Edwars, Leena George, Linzy Houchen-Wolloff, Chris Brightling, Sally Singh. Physical activity heterogeneity in COPD; meaningful analysis of data. Eur Respir J 2016; 48: Suppl. 60, 2050

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