Source: International Congress 2016 – Monitoring airway diseases with clinical tools
Disease area: Airway diseases

Abstract

Aim:The aim of this study is to investigate the effects of an acoustic reminder on medication adherence in lung patients.Methods: In this on-going prospective single-blind randomized controlled trial, in- and outpatients from several hospitals around Basel diagnosed with asthma or COPD and with prescribed inhalative medication were recruited. They must have experienced at least one exacerbation in the previous 12 months. The intervention group is provided with an acoustic reminder for inhalation and receives support calls when the medication is not taken as prescribed.In both groups, adherence was measured with electronic devices, which record date and time of each actuation. We present preliminary data of the first 54 patients (154 patients are planned to enroll) recruited since 2014. Adherence was defined as percentage of days with correct dosing (correct number of prescribed inhalations).Results: Of the 54 (76% male, 67.9±9.1 yrs) patients, 42 (78%) had COPD, 8 (15%) asthma and 4 (7%) asthma-COPD overlap syndrome. Adherence to puff inhalers was higher in the intervention compared to control group (80±19% vs. 51±21%; p<0.001). No difference was found for powder capsules between intervention and control group (92±9% vs. 88±14%; p=0.239). More days with correct dosing were observed for powder capsules compared to puff inhalers (88±12% vs. 66±27%; p<0.001) and for therapy plans with once-daily dosage compared to plans with multiple doses per day (89±13% vs. 66±27%; p <0.001).Conclusion:These results suggest a beneficial effect of regular reminder on the adherence of lung patients. Adherence to once-daily dosage and powder capsules regimens appears to be better.


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Claudia Gregoriano (Liestal, Switzerland), Claudia Gregoriano, Simona Henny-Reinalter, Sabrina Maier, Anna-Lisa Flamm, Thomas Dieterle, Isabelle Arnet, Kurt E. Hersberger, Jörg D. Leuppi. Patients’ adherence to chronic treatment in lung diseases: Preliminary data from a randomized controlled trial. Eur Respir J 2016; 48: Suppl. 60, 1038

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