Ionomycin stimulates a synergistic effect of IL-8 and induced sputum on PMN chemotaxis during COPD Source: Annual Congress 2010 - COPD and asthma: models and human studies Year: 2010
Activation of PAR-2 enhances ICAM-1 expression and IL-8 release in airway epithelial cells Source: Eur Respir J 2002; 20: Suppl. 38, 571s Year: 2002
Thrombin activates mitogen activated protein (MAP) kinase and activated protein-1 (AP-1) to induce interleukin-8 (IL-8) release from airway epithelial cells Source: Annual Congress 2003 - Mechanisms of lung injury: from bench to bedside Year: 2003
Platelet activating factor increases β2 -integrin mediated eosinophil adhesion to ICAM-1 through focal clustering of CD11b Source: Annual Congress 2004 - Genetics and molecular mechanisms of COPD and asthma Year: 2004
Inhibition of LPS-induced neutrophil recruitment in the lungs correlates with modulation of neutrophil CD11b expression using the selective CXCR2 receptor antagonist SB-656933 Source: Eur Respir J 2004; 24: Suppl. 48, 218s Year: 2004
Hypoxia induces IL-18 and neutrophil influx in lung parenchyma possibly mediated by MIP-2 Source: Annual Congress 2012 - The many roads to lung injury Year: 2012
Prostaglandin E2 inhibits NLRP3 inflammasome activation through EP4 receptor and intracellular cAMP in human macrophages Source: International Congress 2015 – Mucosal immunology: what’s new in 2015 Year: 2015
Differential inhibition of PAF- and eotaxin-induced human eosinophil chemotaxis by wortmannin Source: Eur Respir J 2002; 20: Suppl. 38, 30s Year: 2002
Phosphoinositide 3-kinase γ required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung Source: Eur Respir J 2010; 35: 1137-1147 Year: 2010
Neutrophil elastase causes MUC5AC mucin synthesis via a EGF receptor, ERK and NF-kB pathway in A549 cells Source: Eur Respir J 2004; 24: Suppl. 48, 554s Year: 2004
Bronchiectasis disease relevant PAMPs stimulate VEGF and neutrophil elastase release from neutrophils Source: International Congress 2017 – Novel mechanisms in asthma Year: 2017
Stimulation of P2 purinergic receptors induces the release of eosinophil cationic protein and interleukin-8 from human eosinophils Source: Eur Respir J 2003; 22: Suppl. 45, 548s Year: 2003
Eosinophil adhesion to cholinergic nerve cells induces NFκB activation via the interleukin-1 receptor associated kinase (IRAK) pathway and upregulates ICAM-1 expression Source: Eur Respir J 2003; 22: Suppl. 45, 10s Year: 2003
Oncostatin M production and release by FMLP and IL-8 stimulated neutrophils Source: Eur Respir J 2004; 24: Suppl. 48, 550s Year: 2004
Late-breaking abstract: Activation of the macrophage inflammasome by TLR3 ligation potentiates release of IL-8 and IP-10 from alveolar type II epithelial cells via a paracrine cytokine network Source: Annual Congress 2011 - Epithelial cells: role in health and disease Year: 2011
Increased expression of sphingosine-1-phosphate and S1PR2 are associated with attenuated macrophage phagocytosis in COPD Source: Annual Congress 2013 –COPD: experimental biology Year: 2013
TLR2 and TLR4 induced tolerance in alveolar macrophages; differential effect on TNFα and IL-8 release Source: Annual Congress 2012 - Cellular signalling mechanisms in the airways Year: 2012
N-Acetylcysteine inhibits eotaxin and MCP-1 release in human airway smooth muscle cells in vitro through the inhibition of ROS production, resulting in a decrease of p38 MAP kinase activation Source: Eur Respir J 2002; 20: Suppl. 38, 170s Year: 2002
Neutrophil activation in asthma Source: Eur Respir J 2003; 22: Suppl. 45, 400s Year: 2003
Roflumilast potently inhibits CXCL1 mediated neutrophil migration in COPD patients Source: Annual Congress 2011 - COPD: clinical studies and animal cell models Year: 2011