Source: Annual Congress 2002 - Smoking prevention and cessation
Disease area: Airway diseases

Abstract

Smoking cessation has been a major subject of medical research. We examined the efficacy of the following different methods in smoking cessation:
(A) Prolonged treatment with Bupropion HCL (B) combination of Bupropion HCL and non specific psychological group support (NSGT) (C) combination of Bupropion HCL with Cognitive-Behavioural Group Therapy (CBGT), and (D) CBGT only. 327 smokers (mean age 44±]10, 168 males, 159 females) heavily depended (Fangestrom 7,3 ±] 1,9, 35 cigarettes/day) visited the clinic for counceling. 185 were randomised to follow one of the treatment groups for 19 weeks. Smoking attitude and withdrawal symptoms were recorded regularly during the treatment period. Abstinence and success rate (abstinence or 70% reduction of cigarettes) were the final end points of treatment. With the completion of treatment the continuous abstinence rates were 50 % for group A, 60 % for group B, 44% for group C and 24% for group D. According to logistic regression analysis the abstinence and success rates were lower for the group D (odds ratio 0,31, p=0,03) with no statistical difference in between the other groups (odds ratio B:1,5,C:0,8) compared to group A. Higher abstinence was observed in females compared to males (odds ratio 0,39,p=0,03). At 3 months follow up, preliminary results have shown that there was also a less success propability in CBGT group.These results indicate that prolonged treatment with bupropion HCL may offer higher continuous abstinence and success rate compared with the 7 weeks maintainance treatment, irrespectively the combination of any supportive group therapy.

Rating:

Share or cite this content

Citations should be made in the following way:
C. Gratziou, N. Rovina, Z. Athanassa, K. Francis, E. Evangelou, D. Chiotis, Z. Sarlani, K. Efthimiou, T. Kalpakoglou, G. Katsani, A. Roussou, A. Kalantzi, C. Roussos (Greece). Evaluation of prolonged bupropion treatment as an aid in smoking cessation. Eur Respir J 2002; 20: Suppl. 38, 3823

Member's Comments

No comment yet.

Related content which might interest you: Efficacy of bupropion therapy in smoking cessation Source: Eur Respir J 2004; 24: Suppl. 48, 153s Year: 2004 Short or prolonged treatment with bupropion HCL in smoking cessation Source: Eur Respir J 2003; 22: Suppl. 45, 165s Year: 2003 Effectiveness of treatment with bupropion HCL, NRTs and combination in smoking cessation Source: Eur Respir J 2004; 24: Suppl. 48, 156s Year: 2004 Effectiveness of varenicline treatment in a smoking cessation clinic Source: Annual Congress 2009 - Epidemiology of smoking and smoking cessation Year: 2009 Pharmacological treatment for smoking cessation Source: Eur Respir Mon; 2008: 42: 74–97 Year: 2008 Exercise in addition to nicotine replacement therapy improves success rates in smoking cessation Source: Annual Congress 2006 - How to treat tobacco smokers Year: 2006 Higher effectiveness of a longer course of nicotine replacement therapy for smoking cessation Source: Eur Respir J 2006; 28: Suppl. 50, 296s Year: 2006 Comparison of efficacy of varenicline and nortriptyline– Short-term smoking cessation in outpatient setting Source: International Congress 2016 – Emerging issues in smoking cessation and tobacco products Year: 2016 Causes of quitting treatment with varenicline in a smoking cessation clinic Source: Annual Congress 2009 - Epidemiology of smoking and smoking cessation Year: 2009 Improvement of quit smoking rate by combining varenicline and nicotine replacement therapy Source: Annual Congress 2009 - Smoking cessation Year: 2009 Relapse rates following different types of medication treatment through a smoking cessation program Source: Annual Congress 2006 - How to treat tobacco smokers Year: 2006 Predictors of smoking cessation Source: Annual Congress 2009 - Smoking cessation Year: 2009 Efficacy of bupropion SR in a smoking cessation programme for heavy smokers: preliminary results Source: Eur Respir J 2001; 18: Suppl. 33, 167s Year: 2001 Experiencing bupropion hydrochloride in smoking cessation Source: Eur Respir J 2004; 24: Suppl. 48, 156s Year: 2004 Effect of a nicotine free inhalator as part of a smoking cessation program Source: Annual Congress 2010 - Smoking cessation interventions Year: 2010 Factors affecting the success of smoking cessation treatment in a smoking cessation clinic Source: International Congress 2017 – Smoking cessation Year: 2017 Relation between smoking cessation therapy and nicotine withdrawal syndrome Source: Annual Congress 2010 - Smoking cessation interventions Year: 2010 Factors associated with abstinence and effectiveness of a smoking cessation program Source: Eur Respir J 2006; 28: Suppl. 50, 390s Year: 2006 The efficacy of motivational aupport in cigarette cessation treatment Source: Eur Respir J 2005; 26: Suppl. 49, 387s Year: 2005