Source: Annual Congress 2002 - Oncology imaging: CT, MRI and PET
Disease area: Thoracic oncology

Abstract

PET is a promising tool for the descrimination between malignant and benign solitary pulmonary lesions based on original studies made with dedicated PET scanners. However, these are expensive and not so available. Hybrid PET scanners are widely spread and cheaper, but might have a lower sensitivity.The aim of the present study was to compare the diagnostic yield of hybrid and dedicated PET in pulmonary lessions. We also assessed if PET reduced the need for invasive diagnostic procedures.
Methods: All patients with a pulmonary lesion and clinically operable were asked to enter the study. CT-scan of the thorax and abdomen, bronchoscopy or percutaneous needle-aspiration and PET scan were performed within a week. Both a dedicated PET and a Hybrid PET were done on the same day. They were read blinded except for the chest X-ray report. The PET scans were done in two different wards and described consequetively by independent examiners. If any pathological foci were found in any examination further assessments or thoracotomy were performed.
Results: 68 patients have been examined, 22 females and 46 males. Age 22-83 (mean 59) years. The pulmonary nodules was stated as T1: 25, T2:25, T3:5 and T4:9. The final diagnosis was malignant in 50% of patients (87% Nonsmall cell, 13% small cell) and in 50% of patients a non-malignant diagnosis were found. In 80 %was the malignant/nonmalignant diagnosis correctly done by ded.PET and by h.PET 76%. In 0 % was an malignant diagnosis missed by ded. PET and by h.PET it was 3%.Conclusion: Both methods seems to give a high diagnostic yield and an important diagnostic tool in our practice.

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Citations should be made in the following way:
H. K. Enevoldsen, P. Outari, J. Mortensen, A. Eigtved, H. Hansen, H. Vinther, V. Backer, L. Friberg (Odense, Copenhagen, Denmark). Preliminary data of prospective comparison of hybrid PET and dedicated PET in patients with pulmonary lesions. Eur Respir J 2002; 20: Suppl. 38, 3769

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