Source: Annual Congress 2002 - Thoracic oncology: diagnosis and prognosis
Disease area: Thoracic oncology

Abstract

Introduction: Autofluorescence bronchoscopy is more sensitive than white light bronchoscopy in discovering early stage preinvasive lesions. In cases of moderate or severe dysplasias further observation is recommended. Surgical resection is an acceptable therapeutic option for patients with carcinoma in situ, because the majority of these lesions progress to invasive cancer.
Purpose: To review our experience with follow-up autofluorescence bronchoscopy (AFB).
Method: Retrospective analysis of the patients' documentation. Between 04.1999. – 02.2002. 4537 bronchoscopies including 204 AF bronchoscopies with the Storz D-light AF system were performed at our bronchology unit. Follow-up AF bronchoscopies were done in 18 patients (16 male, 2 female, mean age: 57 years). The mean follow-up period was 6.7 months between the 45 surveillance bronchoscopies ( 2.5/patient).
Indications of repeated AFB: control of benign lesions: 4, suspected primary lung tumor: 4, abnormal AFB finding, normal histology: 5, resecability: 5, hemoptysis: 2, metaplasia: 3, dysplasia: 6, stump or anastomosis control: 16.
Results of follow-up AFB: no further autofluorescence abnormality in 6/18 pts, no change of abnormal AF image in 5/18 pts, new AF abnormality in 7/18 pts.
Conclusion: Patients with abnormal AF images should be followed up on a 6 monthly basis. Endobronchial ultrasound as our new diagnostic possibility will help us to determine the exact wall invasion of early stage lung cancers.

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Citations should be made in the following way:
B. Szima, J. Strausz (Torokbalint, Hungary). Follow-up of patients with autofluorescence bronchoscopy. Eur Respir J 2002; 20: Suppl. 38, 3723

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