Endobronchial ultra-sound (EBUS)-assisted transbronchial needle aspiration (TBNA)of extra-luminal lesions in topical anesthesia improve diagnosis compared to TBNA without EBUS

A. Madkour, A. Scherff, B. Khanavkar, Z. Atay, J. Nakhosteen (Bochum, Hannover, Germany)

Source: Annual Congress 2002 - Thoracic ultrasound and photodynamic therapy
Session: Thoracic ultrasound and photodynamic therapy
Session type: Oral Presentation
Number: 3715
Disease area: Thoracic oncology

Congress or journal article abstract

Abstract

Purpose: To evaluate the diagnostic usefulness of EBUS-assisted TBNA in comparison with non-assisted TBNA in patients with extrabronchial lesions. Methods: From Oct. 2000 to Dec. 2001, bronchoscopic EBUS-assisted TBNA using a 21G fenestrated aspiration needle (NA-2C, Olympus) and a 20 MHz radial ultrasonic probe with integrated balloon (Olympus UM-BS 20-26R) was performed in 72 patients with 82 extrabronchial lesions (peribronchial disease, mediastinal adenopathy) under topical anesthesia. The results were compared with our previous study from Jan. to Dec. 1989 on non-assisted TBNA results for 55 extrabronchial lesions using the same needle. Results: EBUS-assisted TBNA was diagnostic in 32/50 mediastinal lymph nodes (LNs) and 27/32 peribronchial lesions, i.e. 59/ 82 (72%) in total. There were 15 inadequate samples, 8 samples were non-diagnostic. The size of LNs in non-diagnosed cases was slightly, but non-significantly smaller compared to the diagnosed LNs. Non-assisted TBNA in 1989 was diagnostic in 18/55(33%) lesions with12 inadequate and 25 non-diagnostic samples. There were no TBNA related complications in both studies. EBUS was well tolerated by most of the patients, prolonging the examination by 12 minutes on average. Conclusion: EBUS assistance improved our diagnostic yield of TBNA in extrabronchial lesions.


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A. Madkour, A. Scherff, B. Khanavkar, Z. Atay, J. Nakhosteen (Bochum, Hannover, Germany). Endobronchial ultra-sound (EBUS)-assisted transbronchial needle aspiration (TBNA)of extra-luminal lesions in topical anesthesia improve diagnosis compared to TBNA without EBUS. Eur Respir J 2002; 20: Suppl. 38, 3715

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