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Stockholm 2002
Wednesday 18.09.2002
Interstitial lung disease
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Usual interstitial pneumonia(UIP):different evolution in Idiophatic pulmonary fibrosis(IPF) in contrast of UIP secondary to other diseases?
P. Monteiro, M. Fonseca, R. Melo, D. Moniz, A. Bugalho de Almeida (Lisboa, Portugal)
Source:
Annual Congress 2002 - Interstitial lung disease
Session:
Interstitial lung disease
Session type:
Oral Presentation
Number:
3678
Disease area:
Interstitial lung diseases
Abstract
The histologic diagnosis of UIP has been related with a poor prognosis with a mean survival of 3 to 5 years. UIP is related not only with IPF but also with other diseases. The authors evaluated 24 patients with UIP: 14 with IPF (group A) and 8 with secondary UIP (group B) due to scleroderma, hypersensivity pneumonitis, rheumatoid arthritis and vasculitis.
Group A had a mean age of 65±]13,4 years wich was significantly higher than group B wich had a mean age of 51±]10,2(
P
=0,03).
Duration of symptoms until our first medical evaluation was also different in group A (19,4 ±]10,2 months) compared to group B (45±]28,5 months).Clinical presentation and severity of restriction were similar in both groups but duration of the disease was significantly higher in group B(
P
=0,02) revealing a slower progression at this group.For that we conclude that although histhology is almost the same at this groups the behaviour and evolution of the disease are significantly different. It seems that secondary UIP has a better prognosis and response to therapy than IPF.
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Citations should be made in the following way:
P. Monteiro, M. Fonseca, R. Melo, D. Moniz, A. Bugalho de Almeida (Lisboa, Portugal). Usual interstitial pneumonia(UIP):different evolution in Idiophatic pulmonary fibrosis(IPF) in contrast of UIP secondary to other diseases?. Eur Respir J 2002; 20: Suppl. 38, 3678
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