Exocytosis of matrix metalloproteinases (MMPs) by pulmonary and systemic polymorphonuclear neutrophils (PMN) in hospital acquired pneumonia (HAP)

C. M. Hartog, J. A. Wermelt, W. Eichler, K. Dalhoff, J. Braun (Luebeck, Germany)

Source: Annual Congress 2002 - Biological disease markers in airways and parenchymal lung disease
Session: Biological disease markers in airways and parenchymal lung disease
Session type: Poster Discussion
Number: 3613
Disease area: Respiratory infections

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
C. M. Hartog, J. A. Wermelt, W. Eichler, K. Dalhoff, J. Braun (Luebeck, Germany). Exocytosis of matrix metalloproteinases (MMPs) by pulmonary and systemic polymorphonuclear neutrophils (PMN) in hospital acquired pneumonia (HAP). Eur Respir J 2002; 20: Suppl. 38, 3613

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Matrix metalloproteinases (MMPs), tissue inhibitor of matrix metalloproteinases (TIMPs) and transforming growth factor-β (TGFβ) expression in small airways (SA) of usual idiopathic pneumonia (UIP), non-specific interstitial pneumonia (NSIP), hip
Source: Annual Congress 2007 - Role of genomics and biological tools in the work-up of interstitial lung disease
Year: 2007


Matrix metalloproteinases (MMPs) and angiogenesis in lung tissue remodeling in different variants of idiopathic interstitial pneumonia (IIP)
Source: Eur Respir J 2007; 30: Suppl. 51, 137s
Year: 2007

Pneumolysin induces release of matrix metalloproteinase-8 and -9 from human neutrophils
Source: Eur Respir J 2009; 34: 1167-1170
Year: 2009



Impact of acute exposure to tobacco smoke on gelatinases in the bronchoalveolar space
Source: Eur Respir J 2008; 32: 644-650
Year: 2008



Production of matrix metalloprotease-9 (MMP-9) by alveolar macrophages (AMs) from smokers: effect of corticosteroids and phosphodiesterase inhibition
Source: Eur Respir J 2001; 18: Suppl. 33, 34s
Year: 2001

Matrix Metalloproteinases (MMPs) in patients with pulmonary tuberculosis (PT) and comorbid COPD
Source: International Congress 2018 – Tuberculosis comorbidities
Year: 2018


Effect of recombinant α-1 antitrypsin (rAAT) and TAPI on neutrophil elastase (NE) and matrix metalloproteinase-9 (MMP9) activity in induced sputum (IS) from healthy smokers and patients with chronic obstructive pulmonary disease (COPD)
Source: Annual Congress 2003 - Progress on therapy for chronic obstructive pulmonary disease
Year: 2003


Elevation of neutrophil collagenase (MMP-8) and elastase during COPD exacerbation
Source: Annual Congress 2008 - Inflammatory trigger mechanisms in asthma and COPD
Year: 2008


Pathogen-dependent MMP-8 and MMP-9 excess in hospital acquired pneumonia (HAP)
Source: Eur Respir J 2002; 20: Suppl. 38, 418s
Year: 2002

Human macrophage elastase (MMP-12) expression in human emphysematous lungs: role in extracellular matrix remodelling in chronic obstructive pulmonary diseases (COPD)
Source: Eur Respir J 2001; 18: Suppl. 33, 501s
Year: 2001

Overexpression of matrix metalloproteinase-8 and -9 in bronchiectatic airways in vivo
Source: Eur Respir J 2002; 20: 170-176
Year: 2002



Matrix metalloproteinases (MMPs) and acute phase proteins (APP) in predicting the efficacy of intensive phase treatment (IPP) in patients with pulmonary tuberculosis (PT)
Source: International Congress 2016 – Treatment management options and costs: vitamin D, Matrix metalloproteinases (MMPs), nutrition, and human genetics
Year: 2016


Role of polymorphonuclear neutrophils (PMN) in Interleukin-1β (IL-1β) processing during bacterial lung infection: Relevance to cystic fibrosis (CF)
Source: International Congress 2015 – Cystic fibrosis: microbiology, immunology and assessment
Year: 2015


Matrix metalloproteinase (MMP)-2 production by fibroblasts and mast cells: the role in pulmonary fibrosis
Source: Eur Respir J 2004; 24: Suppl. 48, 455s
Year: 2004

The role of matrix metalloproteinase- 9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMMP-1) in sarcoidosis and idiopathic pulmonary fibrosis. Correlation with echocardiography
Source: Eur Respir J 2006; 28: Suppl. 50, 745s
Year: 2006

Matrix metalloproteinases in tuberculosis
Source: Eur Respir J 2011; 38: 456-464
Year: 2011



Matrix metalloproteinases and their inhibitors in pulmonary hypertension},
Source: Eur Respir J 2012; 40: 766-782
Year: 2012



High MMP-9 activity characterises pleural tuberculosis correlating with granuloma formation
Source: Eur Respir J 2009; 33: 134-141
Year: 2009



Remodelling of extracellular matrix (ECM) differs between pulmonary adenocarcinoma (Ad) and squamous cell carcinoma (Sq): immunohistochemistry and morphometry of matrix proteins (MPs), matrix metalloproteinases (MMPs), and tissue inhibitors of MMPs (TIMPs
Source: Annual Congress 2008 - Novel targets in the molecular pathology of lung cancer and COPD
Year: 2008


Circulating matrix metalloproteinase-9 (MMP-9) is associated with the extension of lung disease in patients with active tuberculosis
Source: Eur Respir J 2004; 24: Suppl. 48, 35s
Year: 2004