LATE-BREAKING ABSTRACT: Human mesenchymal stem cell exosomes attenuates sepsis-induced acute lung injury via inhibition of oxidative stress and the MAPK-NF-?B pathway

Jie Chen (Beijing, China), Jie Chen, Liangan Chen

Source: International Congress 2015 – Acute critical care: mechanical ventilation: how to limit the damage
Session: Acute critical care: mechanical ventilation: how to limit the damage
Session type: Oral Presentation
Number: 4471
Disease area: Respiratory critical care

Congress or journal article abstractSlide presentation

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Jie Chen (Beijing, China), Jie Chen, Liangan Chen. LATE-BREAKING ABSTRACT: Human mesenchymal stem cell exosomes attenuates sepsis-induced acute lung injury via inhibition of oxidative stress and the MAPK-NF-?B pathway. Eur Respir J 2015; 46: Suppl. 59, 4471

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
LATE-BREAKING ABSTRACT: Activation of MTOR in pulmonary epithelium promotes LPS-induced acute lung injury
Source: International Congress 2016 – Novel mechanisms and therapeutic targets in acute and chronic inflammatory disease
Year: 2016



Cell therapy for the treatment of acute lung injury: Alveolar type II cells or mesenchymal stem cells?
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016

Effects of ceramide pathway inhibition on the inflammatory response in lipopolysacharide-triggered lung injury
Source: International Congress 2015 – Respiratory muscles and airways function: from physiology to clinical implications
Year: 2015

Down-regulation of RIP140 can prevent LPS-induced inflammation and acute lung injury in mice via PPARγ
Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Year: 2015

Mesenchymal stem cell-conditioned medium induces neutrophils apoptosis via inhibition of NF-kB pathway and increases endogenous pulmonary stem cells in endotoxin-induced acute lung injury
Source: International Congress 2015 – The multiple facets of stem and progenitor cells in lung health and disease
Year: 2015

Characterization of ceramide generation kinetics in a lung injury model induced by lipopolysaccharide
Source: International Congress 2015 – Respiratory muscles and airways function: from physiology to clinical implications
Year: 2015

The role of SIRT1 in LPS-induced lung endothelial barrier dysfunction and lung injury in vivo
Source: International Congress 2016 – Molecular targets in pulmonary disease
Year: 2016


Methotrexate reduces acute lung injury in a murine model of sepsis
Source: International Congress 2016 – Infections, sepsis, and pulmonary embolism
Year: 2016


The self-protection effect from ischemia reperfusion lung injury in Adenine-induced renal failure rat model
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014

Effects of S-nitroso-N-acetyl-penicillamine (SNAP) on inflammation, apoptosis and iNOS activity in an experimental model of acute lung injury
Source: International Congress 2015 – Acute critical care: novelties in critical care
Year: 2015


Microvesicles derived from alveolar macrophages mediate epithelial activation via a TNF dependant mechanism
Source: International Congress 2015 – Novel insights into the pathobiology of acute lung injury
Year: 2015

Expression of water and ion channels proteins in acute respiratory distress syndrome from different etiologies
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014

Altered expression of claudin 5 isotype modulates tight junctions permeability in experimental LPS-induced acute lung injury in mice
Source: Annual Congress 2013 –Novel mechanisms in lung injury
Year: 2013


LATE-BREAKING ABSTRACT: The metalloproteinase ADAM8 promotes acute and chronic lung inflammation
Source: International Congress 2015 – Inflammation and remodelling in lung disease
Year: 2015

Erythropoietin inhibits respiratory epithelial cell apoptosis in a model of acute lung injury
Source: Eur Respir J 2009; 33: 1403-1414
Year: 2009



Proton-sensing TDAG8 exhibits the protective role in lipopolysaccharide-induced acute lung injury
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016


Essential oils reduced lung inflammation in a model of acute lung injury
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014

Dexamethasone in patients with acute lung injury from acute monocytic leukaemia
Source: Eur Respir J 2012; 39: 648-653
Year: 2012



Heparin effect in pulmonary cell populations in an in-vitro model of acute lung injury
Source: International Congress 2016 – Studies in airway cell biology
Year: 2016


Effects of VAChT reduction on the time course of lung inflammation in mice with acute lung injury
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016