The mechanism of the inhibition of epithelial sodium channel by tumor necrosis factor-alpha in alveolar type II epithelial cells

Y. Yamagata, T. Yamagata, T. Nishimoto, M. Nakanishi, T. Hirano, K. Matsunaga, H. Nakanishi, Y. Minakata, M. Mune, S. Yukawa (Wakayama, Japan)

Source: Annual Congress 2002 - Airway epithelial cell activation, proliferation and differentiation
Session: Airway epithelial cell activation, proliferation and differentiation
Session type: Poster Discussion
Number: 3533

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Y. Yamagata, T. Yamagata, T. Nishimoto, M. Nakanishi, T. Hirano, K. Matsunaga, H. Nakanishi, Y. Minakata, M. Mune, S. Yukawa (Wakayama, Japan). The mechanism of the inhibition of epithelial sodium channel by tumor necrosis factor-alpha in alveolar type II epithelial cells. Eur Respir J 2002; 20: Suppl. 38, 3533

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The inhibition of amiloride-sensitive current by tumor necrosis factor-alpha in alveolar type II epithelial cells and its signalling mechanism
Source: Eur Respir J 2003; 22: Suppl. 45, 37s
Year: 2003

Mechanism of epithelial Na+ channel (ENaC) inhibition by hypoxia in alveolar epithelial cells
Source: Annual Congress 2012 - New insights into airway epithelial cell physiology
Year: 2012


Activation of alveolar fluid reabsorption in rat lung by tumor necrosis factor and terbutaline is triggered by different mechanisms
Source: Eur Respir J 2004; 24: Suppl. 48, 452s
Year: 2004

Vascular endothelial growth factor mRNA and protein expression in airway epithelial cell lines in vitro
Source: Eur Respir J 2002; 20: 1449-1456
Year: 2002



Surface expression of CD74 by type II alveolar epithelial cells: a potential mechanism for macrophage migration inhibitory factor-induced epithelial repair
Source: Annual Congress 2008 - Border patrol: the alveolar barrier in lung injury
Year: 2008


Modulation of NOS2 expression in co-cultures of human alveolar epithelial cells type II and alveolar macrophages
Source: Eur Respir J 2001; 18: Suppl. 33, 161s
Year: 2001

The effect of vascular endothelial growth factor (VEGF) on primary human cultured type 2 alveolar epithelial (AE2) cell proliferation
Source: Annual Congress 2004 - Cellular injury and repair in the lung
Year: 2004


Inhibition of proliferation of lung cancer cells by CD40 signaling through tumor necrosis factor I
Source: Annual Congress 2008 - Biology and prognosis in thoracic oncology
Year: 2008

The impact of interleukin-2 on the regulation of epithelial sodium channel in A549 cells
Source: Eur Respir J 2004; 24: Suppl. 48, 554s
Year: 2004

Regulation of human adult primary alveolar type II cell surfactant protein production by epithelial growth factors and pro-inflammatory cytokines
Source: Annual Congress 2009 - Pathological remodelling in chronic lung disease: from epithelial-mesenchymal transition to cellular activation
Year: 2009


Physiomer(R) reduces the chemokine interleukin-;8 production by activated human respiratory epithelial cells
Source: Eur Respir J 2001; 18: 661-666
Year: 2001



In vivo blockade of KCa3.1 ion channel alleviates ER stress in type II alveolar epithelial cells and macrophages in pulmonary fibrosis
Source: International Congress 2019 – Translational aspects of idiopathic pulmonary fibrosis
Year: 2019


Effect of in vivo blockade of the KCa3.1 ion channel on type II alveolar epithelial cell turnover in pulmonary fibrosis
Source: International Congress 2018 – Novel insights in the basic and translational research on idiopathic interstitial pneumonias
Year: 2018




N-acetylcysteine reduces tumor necrosis factor-α release by alveolar macrophages of interstitial lung disease in vitro
Source: Annual Congress 2007 - Considerations in the therapeutic approach of interstitial lung disease: oxidative stress and inflammation
Year: 2007


Wnt11 inhibits epithelial-mesenchymal transition induced by TGFb1 in human type II alveolar epithelial cells
Source: Annual Congress 2012 - Fibrogenesis between epithelial injury and fibroblast proliferation
Year: 2012


Anti-inflammatory effect of adenovirus-mediated IκBα overexpression in respiratory epithelial cells
Source: Eur Respir J 2001; 18: 801-809
Year: 2001



Hyperosmotic induction of IL-8 in bronchial epithelial cells is cell volume dependent
Source: Eur Respir J 2001; 18: Suppl. 33, 407s
Year: 2001

PP126 – RANKL contributes to lung tissue repair via promoting type II epithelial cell proliferation
Source: ERS Lung Science Conference 2021
Year: 2021

RANKL contributes to lung tissue repair via promoting type II epithelial cell proliferation
Source: Virtual Congress 2020 – Elucidating the mechanisms underlying lung repair and exploring therapeutic strategies in vitro
Year: 2020




Protein S inhibits the secretion of inflammatory cytokines from alveolar epithelial cells
Source: Annual Congress 2008 - Structural remodelling in COPD
Year: 2008