Effect of simvastatin on steroid-resistence in human epithelial cultured cells: A preliminary study

Luigino Calzetta (Rome, Italy), Luigino Calzetta, Barbara Rinaldi, Giuseppe Gritti, Maria Donniacuo, Giovanna Donnarumma, Maria Gabriella Matera

Source: International Congress 2015 – New models for treating airway diseases
Session: New models for treating airway diseases
Session type: Poster Discussion
Number: 3572
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Luigino Calzetta (Rome, Italy), Luigino Calzetta, Barbara Rinaldi, Giuseppe Gritti, Maria Donniacuo, Giovanna Donnarumma, Maria Gabriella Matera. Effect of simvastatin on steroid-resistence in human epithelial cultured cells: A preliminary study. Eur Respir J 2015; 46: Suppl. 59, 3572

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Differential expression of uPAR in cultured bronchial epithelial cells from asthma patients
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

Regulation of GROα production in human bronchial epithelial cells
Source: International Congress 2016 – Laboratory tests and cell biology in allergy and immunology
Year: 2016


Epithelial to mesenchymal transition in basal progenitor epithelial cells cultured from smokers and COPD patients
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015


Human lung mast cells alter asthmatic airway epithelial cell function
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013


Inhibition of IRAK4 suppresses chemokine release from human bronchial epithelial cells
Source: Annual Congress 2013 –Molecular biology: state-of-the-art 2013
Year: 2013

Synergistic effect of human tubal mesenchymal stem cell (htMSCs) and low level laser (LLL) therapy significantly reduces experimental COPD in mice
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014

Glucocorticoids and indacaterol regulated gene expressions profiling in human bronchial epithelial cells
Source: Annual Congress 2013 –Preclinical models for the development of new drugs for respiratory diseases
Year: 2013

TGFβ-induced epithelial to mesenchymal transition (EMT) as a model of COPD
Source: International Congress 2016 – Novel insights into alveolar and bronchial epithelial cell injury and repair
Year: 2016

The capacity of human airway epithelium to regulate T cell proliferation is reduced in asthma
Source: International Congress 2015 – Asthma mechanisms and management
Year: 2015

Human mast cells and type 2 innate lymphoid cells activate gene expression and mucus composition in human bronchial epithelial cells via IL-13
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

Inhibition of asthma-related immunological responses in mast cells and Th2 cell lines by cultured epithelial cell lines
Source: International Congress 2016 – Mechanisms of disease
Year: 2016

Effect of 14-3-3 protein induction on oncogenic potential of BEAS-2B bronchial epithelial cells
Source: International Congress 2019 – Biology of lung cancer
Year: 2019

Inhibition of phosphodiesterase 4B enhances glucocorticoid-dependent gene transcription in human airway epithelial cells: Implications for the treatment of COPD
Source: Annual Congress 2013 –New drugs in respiratory medicine
Year: 2013


Transcriptome analysis of the human airway epithelium during in vitro differentiation
Source: International Congress 2016 – Studies in airway cell biology
Year: 2016

IL-4 induced changes in the Wnt signalling of bronchial epithelial cells
Source: International Congress 2015 – Asthma mechanisms and management
Year: 2015

Immunosuppressive properties of bronchial epithelial cells are altered in lung transplant recipients: “ex-vivo” model of T cell-allogeneic response
Source: Annual Congress 2013 –New insights into mechanisms of lung allograft dysfunction
Year: 2013


SIRT6-induced activation of autophagy inhibits CSE-induced bronchial epithelial cell senescence
Source: Annual Congress 2013 –New insights into epigenetic mechanisms in the lung
Year: 2013

PINK1-Parkin pathway-mediated mitophagy is involved in cigarette smoke extract (CSE)-induced cellular senescence in human bronchial epithelial cells (HBEC)
Source: International Congress 2014 – Effect of cigarette smoke on cell behaviour: cell biology, signalling and senescence
Year: 2014

Parkin-mediated mitophagy is involved in cigarette smoke extract (CSE)-induced cellular senescence in human bronchial epithelial cells (HBEC)
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013

Both intranasal and intraperitoneal administration of human tubal mesenchymal stem cells (htMSC) ameliorates experimental COPD model
Source: International Congress 2014 – Animal models in respiratory drug development
Year: 2014