Pim1 kinase activity preserves airway epithelial integrity upon house dust mite exposure

Maaike de Vries (Groningen, Netherlands), Maaike De Vries, Laura Hesse, Maarten Van den Berge, Antoon Van Oosterhout, Irene Heijink, Martijn Nawijn

Source: International Congress 2015 – Animal studies of asthma and other inflammatory conditions
Session: Animal studies of asthma and other inflammatory conditions
Session type: Poster Discussion
Number: 1897
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Maaike de Vries (Groningen, Netherlands), Maaike De Vries, Laura Hesse, Maarten Van den Berge, Antoon Van Oosterhout, Irene Heijink, Martijn Nawijn. Pim1 kinase activity preserves airway epithelial integrity upon house dust mite exposure. Eur Respir J 2015; 46: Suppl. 59, 1897

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Loss of bronchial epithelial E-cadherin results in spontaneous airway remodeling and eosinophilic inflammation and exaggerated responses to house-dust mite
Source: International Congress 2015 – The multiple faces of host defense
Year: 2015

Syk mediates airway hyper-responsiveness and airway remodeling in a chronic mouse model of house dust mite induced allergic airways disease
Source: Annual Congress 2013 –Murine models of lung immunology
Year: 2013

Farm dust extract increases the epithelial barrier function of bronchial epithelial cells
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015

Oral presentation: Role of HIF-1? on airway remodelling induced by house dust mite
Source: Lung Science Conference 2010 - Biology of gene-environment interactions in the lung
Year: 2010

YS2: Role of Th9 cells in allergic airway inflammation induced by house dust mite
Source: Lung Science Conference 2011 - Immune system dysregulation in chronic lung disease
Year: 2011

Vitamin D deficiency alters airway structure and function in a chronic house dust mite exposure model
Source: Annual Congress 2013 –Murine models of lung immunology
Year: 2013


House dust mite extract downregulates C/EBP? in asthmatic bronchial smooth muscle cells
Source: Eur Respir J 2011; 37: 50-58
Year: 2011



The non-proteolytic major house dust mite allergen Der p 2 induce proasthmatic responses in bronchial epithelial cells partly through NF-κB and MAPK pathways
Source: Annual Congress 2007 - Mechanisms of inflammation in asthma and rhinitis - from cell cultures to patients
Year: 2007


Human lung mast cells alter asthmatic airway epithelial cell function
Source: Annual Congress 2013 –The pulmonary epithelium: recent developments
Year: 2013


PCDH1: Localization and cell-adhesion in airway epithelium in asthma
Source: International Congress 2015 – Translational studies in airway cell biology
Year: 2015

Inhibitors of apoptosis proteins in asthmatic airway inflammation
Source: Annual Congress 2013 –Asthma: new mechanisms and markers
Year: 2013


Development of an in vitro diesel exposure model for human bronchial epithelial cells
Source: Annual Congress 2013 –Environmental and occupational respiratory diseases: new exposure assessment methods, experimental exposure in animal and humans and mechanisms
Year: 2013


LSC - 2021 - Mesenchymal stromal cells reduce house dust mite induced allergic airway inflammation in a humanised MIF expressing mouse model
Source: Virtual Congress 2021 – New insight into the immunology of allergies, asthma and COPD: from mouse to man
Year: 2021


House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?
Source: Eur Respir J 2010; 35: 1377-1387
Year: 2010



The dynamic change of IL-25 and its receptor expression during allergen challenge in asthmatic subjects
Source: International Congress 2015 – Novel mechanisms and treatments in allergy and asthma
Year: 2015



The capacity of human airway epithelium to regulate T cell proliferation is reduced in asthma
Source: International Congress 2015 – Asthma mechanisms and management
Year: 2015

House dust mite allergen Der f increase bronchial epithelial cell cytokine expression
Source: Eur Respir J 2004; 24: Suppl. 48, 352s
Year: 2004

Role of chronic exposure to cigarette smoke on endoglin/CD105 expression in airway epithelium
Source: International Congress 2015 – Cellular and molecular mechanisms of COPD and emphysema
Year: 2015

Characterisation of lung-resident pericytes in a house dust mite-driven model of asthma
Source: International Congress 2015 – Airway remodelling: recent developments
Year: 2015


Young Investigator session: Overexpression of IRF5 ameliorates house dust mite-mediated airway hyper-responsiveness via macrophage polarisation towards a classically activated phenotype
Source: Lung Science Conference 2013 - Early origins and mechanisms of chronic lung disease
Year: 2013