Vitamin D-mediated expression of the antimicrobial peptide hCAP18/LL-37 and killing of non-typeable haemophilus influenzae (NTHi) is reduced after 14 days exposure to TNF-α and IL-1β in primary bronchial epithelial cells (PBEC)

Jasmijn Schrumpf (Leiden, Netherlands), Jasmijn Schrumpf, Renate Verhoosel, Pieter Hiemstra

Source: International Congress 2015 – The multiple faces of host defense

Session: The multiple faces of host defense
Session type: Oral Presentation
Number: 1785

Disease area: Airway diseases

Rating:

You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Jasmijn Schrumpf (Leiden, Netherlands), Jasmijn Schrumpf, Renate Verhoosel, Pieter Hiemstra. Vitamin D-mediated expression of the antimicrobial peptide hCAP18/LL-37 and killing of non-typeable haemophilus influenzae (NTHi) is reduced after 14 days exposure to TNF-α and IL-1β in primary bronchial epithelial cells (PBEC). Eur Respir J 2015; 46: Suppl. 59, 1785

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.

You must Login to comment this presentation.

Related content which might interest you:

Exposure of a bronchial epithelial cell line (BEAS-2B) to haemophilus influenzae (NTHi) lysate increases TLR-2 and TNF-α synthesis and results in an enhanced PMN adherence to epithelial cells Source: Annual Congress 2008 - Airway infection and host defence Year: 2008
Effect of corticosteroids on epithelial cell response to non-typeable haemophilus influenzae Source: International Congress 2016 – Studies in airway cell biology Year: 2016
Long-term exposure to TNF-alpha and IL-1beta reduces vitamin D-mediated expression of the antimicrobial peptide hCAP18/LL-37 in primary bronchial epithelial cells (PBEC) Source: Annual Congress 2013 –The pulmonary epithelium: recent developments Year: 2013
Effect of roflumilast N-oxide on non-typable haemophilus influenzae (NTHi) interaction with human airway epithelial A549 cells Source: Annual Congress 2011 - Epithelial cell biology Year: 2011
Study on human tracheal bronchial epithelial cells secreting cytokines in vitro by nontypeable haemophilus influenzae Source: Annual Congress 2012 - Scores, biomarkers and risk factors in respiratory infections Year: 2012
Coinfection of chlamydia pneumoniae and haemophilus influenzae enhances interleukin-8 (IL-8) production in human macrophages and alveolar epithelial cells Source: Eur Respir J 2007; 30: Suppl. 51, 405s Year: 2007
Nontypeable haemophilus influenzae (NTHi) and lung oxidative stress Source: Annual Congress 2013 –Translational studies in chronic lung diseases: from bedside to bench Year: 2013
Increased uptake of haemophilus influenzae by primary airway epithelial cells from COPD patients Source: International Congress 2016 – New signalling pathways in COPD Year: 2016
NETosis induced by Haemophilus Influenzae disrupts the lung epithelial barrier Source: Virtual Congress 2021 – Early manifestations of chronic respiratory disease: zooming in at the epithelial barrier Year: 2021
Mycoplasma pneumoniae induces airway epithelial cell expression of MUC5AC in asthma Source: Eur Respir J 2008; 31: 43-46 Year: 2008
Interleukin production by airway epithelial cells after h. influenzae exposure is not related to bacterial growth or passage Source: Annual Congress 2004 - Community acquired pneumonia - epidemiology and host defence Year: 2004
Infection pattern and inflammatory response in acute and persistent nontypeable haemophilus influenzae (NTHi) infection of COPD lung tissue Source: Eur Respir J 2006; 28: Suppl. 50, 841s Year: 2006
Induction of the TGF-beta pseudoreceptor BAMBI by nontypeable haemophilus influenzae (NTHi) and its impact on TGF-beta induced effects Source: International Congress 2014 – Cells, biofilms and biomarkers in respiratory infections Year: 2014
Induction of neutrophil extracellular traps (NETs) by the pneumococcal toxin, pneumolysin (Ply) Source: International Congress 2015 – Advances from translational research in respiratory infections Year: 2015
A subset of COPD patients defined by lung epithelial IL-6 trans-signalling is associated with neutrophilic inflammation and colonization by Haemophilus influenzae Source: International Congress 2019 – Novel mechanisms elucidated by translational studies of COPD Year: 2019
Increased expression of α1-hydroxylase (CYP27B1) in IL-13-exposed primary bronchial epithelial cells (PBEC): Consequences for activation of vitamin D and expression of the antimicrobial peptide hCAP-18/LL-37 Source: Annual Congress 2011 - Epithelial cell biology Year: 2011
Viral infection of macrophages reduces CD36 expression: Implications for phagocytosis of non-typeable haemophilus influenzae Source: International Congress 2015 – Viral infections: basic research and clinical perspective Year: 2015
Chlamydia pneumoniae enhances infection with Haemophilus influenzae, up-regulates TLR2-expression in human lung tissue and leads to enhanced chemokine production after coinfection – a possible mechanism for COPD exacerbations Source: Annual Congress 2008 - New diagnostic methods in viral and atypical infections Year: 2008
The moraxella catarrhalis induced inflammatory response of pulmonary epithelial cells is mediated by activation of EGFR Source: Annual Congress 2008 - Airway infection and host defence Year: 2008
Effect of clarithromycin on rhinovirus-16 infection in A549 cells Source: Eur Respir J 2006; 27: 12-19 Year: 2006