An integrative genomics approach identifies new asthma pathways related to air pollution exposure

Anna Gref (Stockholm, Sweden), Anna Gref, Simon Kebede Merid, Olena Gruzieva, Stéphane Ballereau, Allan Becker, Tom Bellander, Anna Bergström, Yohan Bossé, Matteo Bottai, Moira Chan-Yeung, Elaine Fuertes, Despo Ierodakoniou, Ruiwei Jiang, Michael S. Kobor, Michal Korek, Anita L. Kozyrskyj, Ashish Kumar, Nathanael Lemonnier, Elaina MacIntyre, David Nickle, Ma’en Obeidat, Johann Pellet, Marie Standl, Annika Sääf, Cilla Söderhäll, Carla M.T. Tiesler, Maarten Van den Berge, Judith M. Vonk, Hita Vora, Cheng-Jian Xu, Josep M. Antó, Charles Auffray, Michael Brauer, Jean Bousquet, Bert Brunekreef, W. James Gauderman, Joachim Heinrich, Juha Kere, Gerard Koppelman, Dirkje Postma, Christopher Carlsten, Göran Pershagen, Erik Melén

Source: International Congress 2015 – Genetics, genomics and exposures in asthma and COPD
Session: Genetics, genomics and exposures in asthma and COPD
Session type: Oral Presentation
Number: 1455
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
Anna Gref (Stockholm, Sweden), Anna Gref, Simon Kebede Merid, Olena Gruzieva, Stéphane Ballereau, Allan Becker, Tom Bellander, Anna Bergström, Yohan Bossé, Matteo Bottai, Moira Chan-Yeung, Elaine Fuertes, Despo Ierodakoniou, Ruiwei Jiang, Michael S. Kobor, Michal Korek, Anita L. Kozyrskyj, Ashish Kumar, Nathanael Lemonnier, Elaina MacIntyre, David Nickle, Ma’en Obeidat, Johann Pellet, Marie Standl, Annika Sääf, Cilla Söderhäll, Carla M.T. Tiesler, Maarten Van den Berge, Judith M. Vonk, Hita Vora, Cheng-Jian Xu, Josep M. Antó, Charles Auffray, Michael Brauer, Jean Bousquet, Bert Brunekreef, W. James Gauderman, Joachim Heinrich, Juha Kere, Gerard Koppelman, Dirkje Postma, Christopher Carlsten, Göran Pershagen, Erik Melén. An integrative genomics approach identifies new asthma pathways related to air pollution exposure. Eur Respir J 2015; 46: Suppl. 59, 1455

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Genetics, genomics and a systems approach to asthma
Source: Annual Congress 2008 - “Omics” and systems biology: the promise of future disease understanding
Year: 2008


High-throughput analysis of induced sputum from the U-BIOPRED study using novel proteomic and data mining approaches
Source: Annual Congress 2013 –Origins and diagnosis of asthma
Year: 2013



Transcriptome analysis of controlled and problematic severe childhood asthma
Source: Annual Congress 2013 –Uncontrolled and severe asthma in children
Year: 2013

Combined analysis of gene expression and clinical data in the severe asthma U-BIOPRED cohorts
Source: International Congress 2014 – Novel approaches in transcriptomics and epigenomics in inflammatory lung diseases and lung cancer
Year: 2014



Predicting later asthma in toddlers: Do environmental exposure data improve a clinical tool?
Source: Annual Congress 2013 –Asthma, allergy and lung function: natural history and risk factors in longitudinal studies
Year: 2013


Re-sequencing of PLAUR in severe asthma patients identifies novel variation
Source: International Congress 2014 – Genetics and environmental factors underlying asthma and COPD
Year: 2014

Farm related air pollution and respiratory effects: do recent insights change our perspectives?
Source: International Congress 2017 – Chemical and biological indoor and outdoor pollution
Year: 2017


Indoor home allergen load relates to clinical outcomes in COPD: A metagenomics approach
Source: Virtual Congress 2020 – Clinical characteristics and diagnostic tools for phenotyping asthma and COPD
Year: 2020


Are epigenetic and transcriptomic signatures of air pollution exposure valid biomarkers?
Source: ERS Research Seminar 2017 – The impact of air pollution on respiratory health
Year: 2018


Atmospheric simulation chamber: a versatile tool to get a comprehensive understanding of Air Quality impacts on health in preclinical models
Source: International Congress 2018 – Occupational and environmental lung diseases: air quality and lung damage
Year: 2018




Asthma related to exposure to marine aerosol and industrial pollution: a GIS approach to an epidemiological survey in Livorno
Source: Annual Congress 2007 - The air we breathe at home and at work
Year: 2007



RNA-Seq transcriptome profiling of genes regulated by vitamin D in an asthma model
Source: International Congress 2015 – Immune mechanisms in the human lung
Year: 2015


Is it possible to identify phenotypes of problematic severe asthma in children using fluctuation based clustering?
Source: International Congress 2016 – Paediatric asthma: recurrent, persistent, or severe obstruction and lung function techniques
Year: 2016

Use of GIS technology to analyse the health effect of exposure to heavy traffic pollution in an Italian general population sample
Source: Annual Congress 2013 –Environment and lifestyle: associations with respiratory disease
Year: 2013

The need for a focus on air pollution research in the elderly
Source: Eur Respir J 2003; 21: 92S-95S
Year: 2003



Causal relationships between infections and asthma throughout childhood: A path analysis approach
Source: International Congress 2015 – Highlights in paediatric epidemiology: air pollution, asthma and primary ciliary dyskinesia
Year: 2015

Proteomic analysis of the airway inflammation in work related asthma
Source: International Congress 2014 – Occupational asthma: from childhood to adulthood
Year: 2014


Unbiased cluster analysis of severe asthma based on metabolomics by the U-BIOPRED electronic nose platform
Source: Annual Congress 2013 –Asthma and COPD: diseases with different phenotypes
Year: 2013


“Integrative microbiomics” reveals a disrupted interactome in bronchiectasis exacerbations
Source: Virtual Congress 2020 – Bronchiectasis: epidemiology, endotyping and therapy
Year: 2020




Defining uncontrolled childhood asthma in the global PiCA consortium
Source: International Congress 2016 – Living with asthma around the globe
Year: 2016