The rate of tuberculosis infection in closed contacts of smear positive pulmonary tuberculosis patients

S. Alyasin, A. Alborzi (Shiraz, Iran)

Source: Annual Congress 2002 - Aspects of respiratory disease in primary care
Session: Aspects of respiratory disease in primary care
Session type: Thematic Poster Session
Number: 2992
Disease area: Respiratory infections

Congress or journal article abstract

Abstract

Turberculosis is considered to be one of the most important infectious disease around the world. Those who are in contact with pulmonary tuberculosis might be infected.
In this research, we have collected data and reviewed the value of routine contact procedure in screening for pulmonary tuberculosis (positive sputum) in Shiraz. Some of the factors which were considered to active our objective are age, sex, race and vaccination.
Eighty five individuals suffering from pulmonary tuberculosis (positive sputum) for about 4 years were considered as our index sample, then 626 individuals who are in contact with index sample were notified for tuberculin test. Our index sample consisted of 31 persons with Afghan nationality and the rest were Iranian. Two hundreds ninety five cases with 38% tuberculin positive test were in contact with the former group while three hundreds thirty one cases with 30% tuberculin positive test were in contact with Iranian group.(P<0.05)
In terms of age, 18% were > 5 years old, 30% were in between 6 to 14 years old and 52% were more than 15 years old with 22%, 33% and 38% as an positive tuberculin test results respectively.
In terms of sex in index cases, 31% were infected as a result of being in contact with female index cases while 35% with male index cases (p< 0.3) . As for sex factor in contact cases, tuberculin positive were 37% in male and 30% in female (p<0.3).
Among 626 contant cases, 212 cases showed 5 IU tuberculin skin test indicating induration of more than 10mm (34%).
In conclusion, we have found that tuberculin skin in contact procedure remain a valuable tool in the detection of amount of infection transmitted from index cases to contact cases.


Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
S. Alyasin, A. Alborzi (Shiraz, Iran). The rate of tuberculosis infection in closed contacts of smear positive pulmonary tuberculosis patients. Eur Respir J 2002; 20: Suppl. 38, 2992

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
The rate of TB infection in closed contacts of smear positivepulmonary tuberculosis
Source: Eur Respir J 2004; 24: Suppl. 48, 646s
Year: 2004

The latent tuberculosis infection among household contacts of newly diagnosed patients with sputum-positive pulmonary tuberculosis
Source: Eur Respir J 2003; 22: Suppl. 45, 142s
Year: 2003

Treatment outcomes of smear positive pulmonary tuberculosis cases
Source: Eur Respir J 2005; 26: Suppl. 49, 647s
Year: 2005

A T-cell-based assay for rapid diagnosis of difficult cases of tuberculosis (TB): smear negative pulmonary and extra-pulmonary TB
Source: Eur Respir J 2005; 26: Suppl. 49, 240s
Year: 2005

Latent tuberculosis infection in children in contact with pulmonary tuberculosis patients
Source: Annual Congress 2010 - Tuberculosis in children
Year: 2010


Hair-analysis for acetyl-isoniazid/isoniazid ratio and N-acetyl-transferase-2-genotype in patients on treatment for mycobacterium tuberculosis infection
Source: Annual Congress 2011 - Tuberculosis: from bench to bedside
Year: 2011


Response to M. tuberculosis selected RD1 peptides in Ugandan HIV-infected patients with smear positive pulmonary tuberculosis
Source: Annual Congress 2008 - Interferon-gamma release assay tests for diagnosing tuberculosis infection and disease
Year: 2008


Risk factors for Mycobacterium tuberculosis infection among contacts of pulmonary tuberculosis patients
Source: Annual Congress 2012 - Tuberculous and non-tuberculous mycobacterial infections: epidemiology I
Year: 2012


The relationship between extension of disease in the patients with smear positive pulmonary tuberculosis and hepatotoxicity
Source: Eur Respir J 2006; 28: Suppl. 50, 6s
Year: 2006

Peculiarities in implementation of national tuberculosis program in patients with smear negative pulmonary tuberculosis
Source: Eur Respir J 2004; 24: Suppl. 48, 190s
Year: 2004

Evaluation of D-dimer levels in patients with active pulmonary tuberculosis and latent tuberculosis infection
Source: Eur Respir J 2006; 28: Suppl. 50, 164s
Year: 2006

School contacts of smear positive pulmonary TB and culture positive pulmonary TB
Source: Eur Respir J 2006; 28: Suppl. 50, 487s
Year: 2006

Is smear negative tuberculosis a presentation of new infection in adults?
Source: Eur Respir J 2005; 26: Suppl. 49, 425s
Year: 2005

Frequency of endobronchial tuberculosis in patients with active pulmonary tuberculosis is high
Source: Eur Respir J 2004; 24: Suppl. 48, 33s
Year: 2004

Sputum smear negative pulmonary tuberculosis (PTB) – when should the treatment be started?
Source: Eur Respir J 2006; 28: Suppl. 50, 505s
Year: 2006

HIV positive tuberculosis cases in our center
Source: Eur Respir J 2005; 26: Suppl. 49, 198s
Year: 2005

Over diagnosis of smear negative pulmonary tuberculosis in patients with allergic bronchopulmonary aspergillosis: A study from high tuberculosis burden country
Source: International Congress 2019 – Tuberculosis and comorbidities
Year: 2019


Value of third sputum specimen for microscopic detection of pulmonary tuberculosis in HIV infected patients
Source: Annual Congress 2011 - Tuberculosis in immunocompromised hosts
Year: 2011

Mycobacterial non-tuberculosis infection in patients operated on for pulmonary tuberculosis
Source: Virtual Congress 2020 – Thoracic surgery: lung cancer and infectious disease
Year: 2020


Role of 2-month sputum smears in predicting culture conversion in pulmonary tuberculosis
Source: Eur Respir J 2011; 37: 376
Year: 2011