Undiagnosed asthma as a predisposition for lower respiratory infection
B. Karadag, T. Ozkozaci, S. Uyan, K. Terekli, F. Karakoc, R. Hamutcu, I. Akpinar, O. Ceran, E. Dagli (Istanbul, Turkey)
Source: Annual Congress 2002 - Miscellaneous respiratory infections in children
Session: Miscellaneous respiratory infections in children
Session type: Thematic Poster Session
Number: 2096
Disease area: Paediatric lung diseases
Abstract In an attempt to investigate the predisposing effect of undiagnosed asthma in development of lower respiratory tract infections, 41 children admitted to hospital with pneumonia between January 1996-March 1999 were recruited into the study retrospectively. Personal and family respiratory history, dates and duration of admission, details of the diagnosis and subsequent follow up were noted. Pneumonia was a clinical diagnosis confirmed in all cases on independent review of chest x-ray films. ISAAC questionnaire for asthma was applied to the parents by telephone call. The median interval from admission to this follow up was 60 months ( range 35-73 months ). The children's median age at admission was 12 months (range 1-168 months). Cumulative prevalence of asthma was found to be 34.1%. While 9.8% of the patients had at least one wheezing episode before admission, 19.5% had wheeze in the last year. There was no relationship betweeen asthma development and family history of asthma or atopy ( p>0.05). Mean age of the patients wheezed after pneumonia was significantly lower than the others at admission (46.5 48.8 vs. 20.5 26.9 months) (p<0.05). A considerable proportion of children presenting with pneumonia either already have undiagnosed asthma or subsequently develop asthma.The high cumulative prevalence of asthma suggests that careful follow up of such children is required.
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B. Karadag, T. Ozkozaci, S. Uyan, K. Terekli, F. Karakoc, R. Hamutcu, I. Akpinar, O. Ceran, E. Dagli (Istanbul, Turkey). Undiagnosed asthma as a predisposition for lower respiratory infection. Eur Respir J 2002; 20: Suppl. 38, 2096
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