Source: Annual Congress 2002 - Physiotherapy: assessment and outcome in healthy subjects and patients with chronic lung disease
Disease area: Airway diseases

Abstract

Incremental threshold loading (ITL) has been proposed as a test of inspiratory muscle endurance. The aim of our study was to analyze the regional pulmonary ventilation during the ITL through the pulmonary scintigraphic. Ten female volunteers with age 25,29 ±] 1,38 yrs, weight 54,86 ±] 7,17 kg, height 1,62 ±] 0,08 cm, maximal inspiratory pressure (Pimax) -85,71 ±] 12,88 and vital capacity (VC) 511,03 ±] 114,21 was submitted to 99mTc-DTPA radioaerosol inhalation generated by a jet nebulizer, and connected to the linear loading system (THRESHOLD®). The inhalation lasted 16 min and an image was taken at each 4 min, generating four images with loads of zero, 10, 20 and 30 cmH2O. In order to analyze aerosol deposition (AD) region of interest (ROIs) were delimited one to each lung, and the lugs were subdivided in vertical and horizontal gradient. AD increase when the load was increased. Right lung vertical gradient was larger at the medium third in all phases. For the left lung in the standard phase, the AD was larger in the medium and inferior third. For these loadings: 10, 20 and 30 cmH2O the medium third presented larger deposition. The right lung horizontal axis analysis showed larger AD in the intermediate and central segment in all phases. In the left lung the largest deposition occurred in the intermediate third for the standard, 10 and 20 cmH2O loadings. The 30 cmH2O loading presented larger AD in the intermediate and central segments. The findings suggest that during ITL test occur larger AD in medium third in both lungs

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E. Nobre, A. Dornelas de Andrade, F. Lopes, A. L. Gusmao, L. Cordeiro, P. Marinho, N. Moraes, M. D. G. Rodrigues-Machado (Recife, Brazil). Regional pulmonary ventilation during inspiratory muscles endurance test. Eur Respir J 2002; 20: Suppl. 38, 1159

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