Source: Annual Congress 2002 - Diagnosis of tuberculosis
Disease area: Respiratory infections

Abstract

We evaluated the clinical course and thorax high resolution computerized tomography (HRCT) findings and clinical- radiological correlation of new, recurrent and multidrug resistant (MDR) cases of 65 pulmonary tuberculosis patients (59 male, 6 female) who referred to our hospital between March 2OOO- November 2OOI. The mean age of patients was 31.8-+1.2 (18-67). Twenty-three patients were classified as new, 20 as recurrent and 22 as MDR tb. Age, occupation, symptoms, the duration of symptoms, existence of other medical problems, bacteriological and radiological findings were evaluated using chi-square and Fischer tests for statistical significance. Diagnosis was established by pleural and lung biopsies in 5 patients who did not have sputum analysis. All the other patients had sputum analysis positive for tuberculosis. The most common symptoms in patients were cough (91%) , sputum (78%) and sweating (61%) whereas hemoptysis was the most prominent symptom (44%) in new tb. Patients. In spite of no statistical significance the most common HRCT findings in all groups were centrilobular nodules, cavitation, fibrosis, interlobular septal thickening, air space consolidation respectively. We conclude that HRCT is a valuable diagnostic method especially in diagnosing smear negative tb. patients due to its ability to obtain thin cross sections and to find out fine nodularities. Its sensitivity reaches to 96% in centrilobular nodules. We determined no specific radiologic sign that helped differ the new, recurrent and MDR tb cases. There was no statistically significant difference between groups with respect to age, occupation, symptoms, duration of symptoms, existence of other medical problems, bacteriologic properties and clinical findings did not corralate with radiologic findings.

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Citations should be made in the following way:
M. Ceran, G. Dabak, F. Sungun, E. Ozturk, A. Saygi (Istanbul, Turkey). The clinical and radiological comparison of new, recurrent and multidrug resistant cases of pulmonary tuberculosis. Eur Respir J 2002; 20: Suppl. 38, 1075

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