Aspects of diagnosis and treatment in pulmonary tuberculosis in children
N. Brinza, S. Bodi, E. Chistruga, L. Savin, D. Diculencu (Iasi, Romania)
Source: Annual Congress 2002 - Diagnosis of tuberculosis
Session: Diagnosis of tuberculosis
Session type: Thematic Poster Session
Number: 1074
Disease area: Respiratory infections
Abstract Pulmonary tuberculosis is a very great problem because the diagnosis is complicate and the treatment is controversial. The aim of this study is to reveal the profile of the 269 children treated in our hospital, from January to December 2000 ( 8 median age, sex male/ female 41/69 ). The surveyed parameters include: the history of BCG vaccination, the intrafamilial tuberculosis contact, the size of PPD induration, the microbiological results, the chest X-ray, the associated affections, the treatment and the follow-up. 97 (36%) children were diagnosticated with tuberculosis disease, 136 (50%) with tuberculosis infection and 38(14%) with tuberculosis contacts. 41(42%) children had a microbiological evidence of tuberculosis ([dsquote]definite[dsquote] tuberculosis disease); 56(48%) were [dsquote]probable[dsquote] tuberculosis disease (diagnosis based on epidemiological, clinical and radiological criteria). The chest radiographs of 56(48%) patients showed abnormal mediastinum (suspecting intratoracic tuberculous lymphadenopathy) and of 41(42 % ) cases atypical changes. 17 cases were tuberculosis disease and AIDS, and 2 cases were MDR tuberculosis - AIDS . All cases with tuberculosis disease commenced the treatment in accordance with WHO recommandations (DOTS).Chemoprophylaxis was used in the tuberculosis infection and contact groups.Epidemiological, clinical and radiological criteria are not sufficient for clarifying the diagnosis of [dsquote]probable[dsquote] tuberculosis disease and the difference between tuberculosis disease and tuberculosis infection.The utilisation of complementary investigations (CT scan, flexible bronchoscopy etc.) in these cases would eliminate an inadequate antituberculosis treatment generator of adverse effects and resistance of M. tuberculosis.
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N. Brinza, S. Bodi, E. Chistruga, L. Savin, D. Diculencu (Iasi, Romania). Aspects of diagnosis and treatment in pulmonary tuberculosis in children. Eur Respir J 2002; 20: Suppl. 38, 1074
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