Source: Annual Congress 2002 - Diagnosis of tuberculosis
Disease area: Respiratory infections

Abstract

The two-step tuberculin skin test (TST) decreases the misinterpretation of a [dsquote]boosted reaction[dsquote] as a recent infection with Mycobacterium tuberculosis in candidates for serial TSTs. TST results of 983 person which included in a surveillance program mostly among health care workers were reviewed. After completion a questionnaire, subjects were looked for BCG scar and given 5 TU, 01 ml tuberculin solution with Montoux technique. Transverse indurations were measured on 48-72 hours and 5-7 days with both palpation and [dsquote]ball-point pen[dsquote] methods. On day 7, a second TST was given when the first test result was below 10 mm. Boosting was defined as an increase of >= 6 mm and from < 10 to >= 10 mm. Of those subjects tested, 884 (89.9%) returned for the evaluation. Of those 884 subjects, 200 (22.6%) had a test result below 10 mm on 48-72 hours. Of those 200, 169 (845%) returned on day 5-7 and 31 of them (18.3%) were slow reactor (increased to > 10 mm). Of those subjects, 138 were eligible for and 122 of them were given the second TST. Of those 122 subjects, 110 (90.2%) returned for the third evaluation and 16 of them (14.5%) were classified as boosted. These results suggest that two-step TST must be done for correct coding the results in Turkish people which have high BCG vaccination rate.

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Citations should be made in the following way:
C. Karlikaya (Edirne, Turkey). Slow reaction and boosting rate on tuberculin skin test in a Turkish population. Eur Respir J 2002; 20: Suppl. 38, 1072

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