Validation of a new version of the chronic respiratory questionnaire (CRQ): the self-administered standardized CRQ
H. J. Schünemann, G. G. Guyatt, E. Ståhl, D. Stubbing, M. J. Mador, D. McKim, P. Austin, R. Goldstein (Hamilton, Canada; Buffalo, United States Of America; Lund, Sweden)
Source: Annual Congress 2002 - Assessment of lung function, telemonitoring and quality of life
Disease area: Airway diseases
Abstract Background: The Chronic Respiratory Questionnaire (CRQ) is a valid and responsive instrument for assessment of health related quality of life (HRQL) in patients with COPD. Criticism of the original CRQ includes its requirement for interviewer administration and its individualized evaluation of dyspnea. Objectives: To compare a novel self-administered version of the CRQ (saCRQ) with the original CRQ and to compare the original individualized (based on the most important activities causing dyspnea) with a standardized dyspnea CRQ domain. Methods: We randomized patients with chronic airflow limitation (mean age 66.9 years, mean FEV1% 42.2%) to receive either the interviewer (n=24) or the self-administered CRQ (n=25) before starting a respiratory rehabilitation program. All patients completed individualized and standardized dyspnea questions and additional HRQL instruments. Results: There were no significant differences in mean scores between the original CRQ and the saCRQ on the four domains (individualized dyspnea: 3.20 vs 3.34, p=0.59; emotional function: 4.60 vs 4.42, p=0.67; fatigue: 3.60 vs 3.57, p=0.92; mastery: 4.47 vs 4.63, p=0.71) or the novel standardized dyspnea domain (4.07 vs 3.97, p=0.83). As expected, mean scores for the standardized dyspnea questions were higher than for the individualized questions (4.02 vs 3.27, p<0.01), but scores were highly correlated (r=0.67, p<0.01). Conclusions: The saCRQ compares well with the original CRQ but does not require presence of an interviewer. Standardizing dyspnea questions could maintain measurement properties and further facilitate use of the saCRQ in clinical studies.
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H. J. Schünemann, G. G. Guyatt, E. Ståhl, D. Stubbing, M. J. Mador, D. McKim, P. Austin, R. Goldstein (Hamilton, Canada; Buffalo, United States Of America; Lund, Sweden). Validation of a new version of the chronic respiratory questionnaire (CRQ): the self-administered standardized CRQ. Eur Respir J 2002; 20: Suppl. 38, 1004
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