Evaluation of a specific container for the transport of arterial blood gases to minimize the pre-analytic errors

M. Lambraña, F. Burgos, J. L. Valera, J. L. Marin, J. Casademont (Barcelona, Spain)

Source: Annual Congress 2002 - Assessment of lung function, telemonitoring and quality of life
Session: Assessment of lung function, telemonitoring and quality of life
Session type: Thematic Poster Session
Number: 998
Disease area: Pulmonary vascular diseases, Respiratory critical care

Congress or journal article abstract

Abstract

The pulmonary gas exchange assessment requires of an appropriate measurement of the arterial blood gases(ABG). The pre-analytic factors is responsible for most of variability of the ABG's and the time delay in the transportation of samples or within the laboratory and the temperature in which has been stored, are the most frequent and important source of error. To minimize the variability of the ABG, a specific container was designed to keep samples to 4[degree]C of temperature and improving the system of transport. The container is manufactured in plastic (policarbonate), resistant to low temperatures that it allows keep and transport 8 ABG syringes. We included 40 consecutive patients admitted to our intensive care that underwent treatment with invasive mechanical ventilation and all of them carry out an arterial catheter line. Five serial samples (arterial blood, 2 ml) were obtained from each patient with a 2.5 ml plastic syringe with heparin (1%). All air bubbles were extracted from the samples and it was sealed with a rubber plug. Five groups were made for patient: A) 4[degree]C, analysis < 15 min; B) 4[degree]C, analysis 30 min; C) ambient T, analysis 30 min; D) 4[degree]C, analysis 60 min and E) ambient T, analysis 60 min. A significant drop was observed in the PaO2 (p<0.001) and an increase in the PaCO2 among the group E (ambient temperature) and the A,B,D (using the specific container). The mean and SD of the groups E and A,B,D, were (PaO2 87±]20 vs 95±]25 mmHg) and (PaCO2 43±]9 vs 42±]9 mmHg) respectively. This container allow a comfortable transport without the inconveniences of an ice and water container and maintain the samples at 4ºC during 1 hour, minimizing the error induced by the time delay in the measurement of the arterial blood gases.


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M. Lambraña, F. Burgos, J. L. Valera, J. L. Marin, J. Casademont (Barcelona, Spain). Evaluation of a specific container for the transport of arterial blood gases to minimize the pre-analytic errors. Eur Respir J 2002; 20: Suppl. 38, 998

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