Source: Annual Congress 2002 - Assessment of lung function, telemonitoring and quality of life
Disease area: Airway diseases

Abstract

Dynamic airway deformation essentially differs at the patients with obstructive and restrictive pathology. FEV PEF (expiratory volume in the moment of peak expiratory flow) characterizes a degree of deformation of lungs and respiratory ways to the moment of achievement PEF. The aim of our study was comparison the index FVC/ FEV PEF (calculated from standard spirometry parameters [dfoquote]MasterScreen[dfcquote], E.Jaeger) in nonsmoking healthy subjects, COPD patients and patients with idiopathic pulmonary fibrosis (IPF).
The first research at 15 healthy (average age 39±]3), 64 COPD patients (average age 53±]1) and IPF patients (average age 38±]3) has shown, that the index FVC/ FEV PEF healthy was
10±]0,4, at the IPF patients it decreased - 6±]1, and at the COPD patients was sharply increased - 46±]6. Thus at the COPD patients its absolute meaning was increased with severity of airflow limitation, and at the IPF patients decreased with reducing TLC. This index was used by us for the analysis 9 762 spirometry protocols and this experience allows us to recommend it for differential diagnostics of obstructive and restrictive types of ventilatory defects, provided that all rules of spirometry performance of research are observed.

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Citations should be made in the following way:
M. Y. Kameneva, W. K. Kuznetsova, E. S. Aganezova, G. A. Lubimov (St-Petersburg, Moscow, Russia). New opportunities for spirometry in differential diagnostics of obstructive and restrictive ventilatory defects. Eur Respir J 2002; 20: Suppl. 38, 990

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