Source: Annual Congress 2002 - Chest trauma, airways and miscellaneous
Disease area: Thoracic oncology

Abstract

Almost a half of child with different thyroid cancer has an aggressive behavior: lymph node and distant metastases, local invasion. The aim of the study was to investigate and evaluate surgical options of treatment of thyroid cancer with direct invasion to larynx and trachea in children.
Patients and methods. During 1986-1997 was operated 229 children. In 55 (18,3%) cases was airway involvement of differentiated thyroid carcinoma and respiratory disoders. Patiens age ranged from 3 to 18 years (main age-10,7)with main-femail ratio 1:1. Most have papillary variant. 4 patients have been previously operated had recurrent cancer. The trachea was involved in all patients. Cervical muscles and lymph node metastasis, esophagus and major vessels were simultaneously resected in 91,01% of patients. Types of surgical resection performed: [dsquote]shave[dsquote] excision (n=50), incomplete excision (n=1), complete tumor removal with part of airway (n=4). The [dsquote]shaving[dsquote] was performed in the superficial involvement of larynx and trachea. Palliative procedures were done due to the extent of tumor. In 4 cases thyroidectomy was combined with trachea window resection (1), circular and irregular-shaped laryngo-tracheal resection (3).
Results. There was no postoperative mortality among patient with laryngotraheal resection with median survival 110,6 month. Total 5-year survival was 94,54%.Total postoperative mortality rate made up 7,27%.
Conclusion. In superficial invasion only [dsquote]shaving[dsquote] without resection is the treatment of choice. Combined resection of the thyroid gland and major airways is technically feasible and provides good local control of the disease, good voice and free respiration improve the quality of life.

Rating:

Share or cite this content

Citations should be made in the following way:
Y. G. Bondarenko, M. M. Bagirov (Kiev, Ukraine). Airway invasion in childhood thyroid carcinoma. Eur Respir J 2002; 20: Suppl. 38, 980

Member's Comments

No comment yet.

Related content which might interest you: Neuroendocrine lung carcinoma in a child Source: Annual Congress 2009 - Various diagnostic aspects in lung cancer and rare lung tumours Year: 2009 Neuroendocrine carcinoma of the lung in a child Source: Eur Respir J 2005; 26: Suppl. 49, 537s Year: 2005 Thyroid carcinoma invading the trachea Source: Annual Congress 2010 - Video-assisted thorascopic surgery, novel technical devices and tracheal problems Year: 2010 Diagnosis of testicular embryonal carcinoma by bronchial biopsy Source: Eur Respir J 2002; 20: Suppl. 38, 466s Year: 2002 Borderline early squamous cell lung cancer Source: ISSN=ISSN 1810-6838, ISBN=, page=157 Year: 2004 Angiogenic squamous dysplasia: highly associated with squamous cell lung carcinoma Source: Annual Congress 2006 - Biological features, lung function and treatment of lung cancer Year: 2006 Cellular atypia in bronchial washings and risk of bronchogenic carcinoma Source: Eur Respir J 2002; 20: Suppl. 38, 185s Year: 2002 Bronchial bacterial colonization in patients with resectable lung carcinoma Source: Eur Respir J 2002; 19: 326-332 Year: 2002 Management of oesophageal carcinoma with associated lung tuberculosis Source: Eur Respir J 2002; 19: 784-785 Year: 2002 Bronchial endoscopy in the diagnosis and treatment of carcinoid, cylindroma and bronchial muco-epidermoid tumors Source: Eur Respir J 2002; 20: Suppl. 38, 78s Year: 2002 Interventional bronchoscopy in locally advanced thyroid cancer with tracheal invasion Source: International Congress 2019 – Interventional pulmonology: re-sculpting the airway Year: 2019 Lung metastasis of thyroid carcinoma: misunderstanding of existing pathology Source: Eur Respir J 2001; 18: Suppl. 33, 398s Year: 2001 Expression of protein onkological marker onkoprobe in peripheral blood in cases of tracheal invasion and lung metastases of thyroid carcinoma Source: Eur Respir J 2002; 20: Suppl. 38, 466s Year: 2002 Neuroendocrine tumours of the lung other than SCLC Source: ERS webinar 2021: Neuroendocrine tumours of the lung other than SCLC Year: 2021 A suspected bronchial ?carcinoma Source: Breathe, 13 (4) e114; 10.1183/20734735.010317 Year: 2017 Small cell lung cancer with the initial manifestation of parotid gland metastasis Source: Eur Respir J 2004; 24: Suppl. 48, 533s Year: 2004 Early surgical resection for stage I high-grade neuroendocrine caricinoma of lung Source: International Congress 2016 – Lung cancer: therapeutic modalities, re-staging, and follow-up Year: 2016 Pulmonary TB/pulmonary carcinoma Source: Eur Respir J 2006; 28: Suppl. 50, 507s Year: 2006 Prevalence of angiogenic squamous dysplasia in bronchial biopsies from patients with bronchogenic carcinoma who underwent whitelight bronchoscopy Source: Eur Respir J 2007; 30: Suppl. 51, 290s Year: 2007