Vehicle exhaust exposure in an incident case-control study of adult asthma

L. Modig, B. Forsberg, L. Nyström (Umeå, Sweden)

Source: Annual Congress 2002 - Exposure to chemicals
Session: Exposure to chemicals
Session type: Thematic Poster Session
Number: 867
Disease area: Airway diseases

Congress or journal article abstract

Abstract

The main purpose of this study was to determine the role of moderate exposure to vehicle exhaust fumes for the development of asthma among adults living in the municipality of Luleå, in the north of Sweden. Furthermore, to investigate the relation between NO2 concentrations and traffic flow. The study population comprised 199 cases and 196 controls. NO2 levels and traffic flow were used to indicate the exposure to exhaust fumes for each dwelling. NO2 was measured indoors and outdoors during a period of seven days whereas traffic flow was estimated by summing up traffic counts of every road passing through zones with different radius created around the dwellings. Residences were divided into subclasses depending on the intensity of traffic within the zone. There were no significant associations between high levels of NO2 either inside or outside the dwellings, and incident asthma. When the highest exposure class was compared with the lowest, OR was 1.12 (95% CI 0.43-2.93) for NO2 indoors and OR was 0.96 (95% CI 0.36-2.54) for NO2 outdoors. When the comparisons were made for traffic flow, no consistent effects were observed. The correlation between outdoor NO2 and traffic flow was low, r= 0.29-0.33. These results show no association that suggests vehicle exhaust fumes to be a cause for developing adult asthma.


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L. Modig, B. Forsberg, L. Nyström (Umeå, Sweden). Vehicle exhaust exposure in an incident case-control study of adult asthma. Eur Respir J 2002; 20: Suppl. 38, 867

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