Single and repeat dose safety and pharmacodynamics studies with the selective intranasal TLR7 agonist GSK2245035 Source: International Congress 2014 – Biomarkers of asthma and clinical immunology Year: 2014
Neuronal toll-like receptor (TLR) 7 expression and function in human airways Source: International Congress 2014 – Novel approaches to human studies in allergy and asthma Year: 2014
Characterization QAW039 and QAV680, two novel, potent and selective CRTh2 antagonists Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology Year: 2014
QAW039, a slowly dissociating CRTh2 antagonist with potential for improved clinical efficacy Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology Year: 2014
ARRY-502, a potent, selective, oral CRTh2 antagonist reduces Th2 mediators in patients with mild to moderate Th2-driven asthma Source: International Congress 2014 – Novel approaches to human studies in allergy and asthma Year: 2014
Human T-lymphocytes are affected by notch ligands in vitro Source: International Congress 2014 – Novel approaches to human studies in allergy and asthma Year: 2014
Immune modulation of the T-cell response in asthma through Wnt10b Source: International Congress 2014 – Exploring molecular mechanisms of allergy and asthma in animal models Year: 2014
Preclinical characterization of CPL-302-201, a novel, highly potent and selective PI3Kδ inhibitor for the treatment of inflammatory disorders Source: International Congress 2014 – New treatments for cough, asthma, COPD and ILDs Year: 2014
TLR 7/8 agonist resiquimod alleviates murine allergic asthma through IL-27 production and up regulation of B7-H1 on antigen presenting cells Source: International Congress 2015 – Animal studies of asthma and other inflammatory conditions Year: 2015
Safety, tolerability and pharmacokinetics of an oral competitive reversible CRTh2 antagonist, QAW039, in healthy subjects Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology Year: 2014
Safety, tolerability and pharmacokinetics of QAV680, an oral CRTh2 antagonist, in healthy subjects Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology Year: 2014
Low level laser in monotherapy or in combination with leukotriene receptor antagonists in the treatment of allergic lung inflammation Source: International Congress 2015 – Chronic airway disorders: miscellaneous aspects Year: 2015
TLR7 and TLR9-activated inflammation is differentially regulated in asthma Source: Annual Congress 2013 –Asthma Year: 2013
Osteopontin binds and modulate the antibacterial action of eosinophil-recruiting chemokines during allergic inflammation Source: International Congress 2015 – Immune mechanisms in the human lung Year: 2015
Anti-inflammatory effects of the novel PDE4 inhibitor CHF6001 on virus inducible cytokines Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology Year: 2014
Eosinophilic airway inflammation is associated with increased TLR2 and TLR4 expression in adult asthmatics Source: International Congress 2014 – TH17 and other acute asthmatic responses Year: 2014
Overproduction of soluble alpha2beta1 integrin in a guinea-pig model of chronic asthma Source: International Congress 2014 – Exploring molecular mechanisms of allergy and asthma in animal models Year: 2014
Pre-clinical characterization of RP3128, a novel and potent CRAC channel inhibitor for the treatment of respiratory disorders Source: Annual Congress 2013 –New drugs in respiratory medicine Year: 2013
RIG-I receptors induced by dsRNA challenges in an HDM-mouse model of asthma exacerbation Source: International Congress 2014 – Exploring molecular mechanisms of allergy and asthma in animal models Year: 2014
ALX-0962, an anti-IgE Nanobody® with a dual mode of action Source: Annual Congress 2013 –Novel drugs for the treatment of asthma and COPD Year: 2013