Lung functions damage and pleural thickenings in Czech workers exposed to asbestos
J. Lebedová, B. Dlouhá, L. Rychlá, M. Brabec, J. Neuwirth, D. Pelclová, Z. Fenclová, H. Benáková (Prague, Czech Republic)
Source: Annual Congress 2002 - Asbestos and silica
Session: Asbestos and silica
Session type: Thematic Poster Session
Number: 842
Disease area: Interstitial lung diseases
Abstract Examination of lung functions and HRCT of the chest was performed in 135 persons, previously exposed to asbestos, who had no signs of parenchymal fibrosis on the chest radiograph. On the basis of the HRCT finding, subjects were divided into three groups: 1. subjects with circumscribed pleural thickening (n = 52, mean exposure 20.2 years), 2. subjects with diffuse pleural thickening (n=31, mean exposure 27.3 years) and 3. subjects without signs of pleural thickening on the HRCT (n=52, mean exposure 16.8 years). In all groups of persons, static ventilatory parameters were examined by bodyplethysmography, including the TLC, dynamic ventilatory parameters (curve flow-volume), flow resistances and DLCO. Also alpha1antitrypsine in serum was measured. Among all three studied groups of subjects, significant differences were seen only in FVC, TLC, VC, FEV1, FEF50, FEF25/75. Alpha1antitrypsine did not significantly influence the ventilatory parameters. In 43.7% of the whole cohort, signs of the initial parenchymal fibrosis were found. After the correction for the parenchymal fibrosis, a significant difference was seen only in TLC between the two groups of subjects with pleural thickenings (p=0.0124) and the group of subjects without pleural thickenings. Conclusion : TLC is probably the best predictor for the estimation of the occurrence of pleural thickenings in persons exposed to asbestos. Ministry of Health Project IGA NJ6081-3/2000 and Ministry of Education Project J13/98 111100002 and 111100005.
Rating:
You must login to grade this presentation.
Share or cite this content
Citations should be made in the following way:
J. Lebedová, B. Dlouhá, L. Rychlá, M. Brabec, J. Neuwirth, D. Pelclová, Z. Fenclová, H. Benáková (Prague, Czech Republic). Lung functions damage and pleural thickenings in Czech workers exposed to asbestos. Eur Respir J 2002; 20: Suppl. 38, 842
You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
Related content which might interest you:
Related content which might interest you:
Lung function impairment in asbestos exposed workers Source: Eur Respir J 2002; 20: Suppl. 38, 126s Year: 2002
Nonmalignant pleural lesions due to environmental exposure to asbestos: a field-based, cross-sectional study Source: Eur Respir J 2005; 26: 875-880 Year: 2005
A novel hypothesis in benign pleural thickening in asbestos exposed patients Source: Annual Congress 2013 –Occupational respiratory diseases: obstructive, interstitial lung diseases and methods of diagnosis Year: 2013
Pleural plaques in dentists from occupational asbestos exposure Source: Annual Congress 2009 - Old and new topics in environmental and occupational lung disease Year: 2009
Pleural neoplasms – linkage with professional asbestos exposure Source: Eur Respir J 2006; 28: Suppl. 50, 702s Year: 2006
Pleural plaques and lung function in asbestos-exposed workers free from pulmonary fibrosis Source: Annual Congress 2011 - Mineral dusts Year: 2011
Prevalence of pleural plaques, pulmonary fibrosis and isolated pulmonary nodules in a large French cohort of retired asbestos workers screened by HRCT Source: Eur Respir J 2007; 30: Suppl. 51, 159s Year: 2007
Asbestos bodies in the sputum of asbestos workers: correlation with occupational exposure Source: Eur Respir J 2002; 20: 1167-1173 Year: 2002
Lung function and radiological findings in a group of fibre-exposed asbestos workers Source: Eur Respir J 2002; 20: Suppl. 38, 127s Year: 2002
Functional respiratory impairments and their relation to p small round opacities and lung emphysema in workers exposed to quartz, asbestos and mixed dust Source: Annual Congress 2009 - Occupational exposures and disease II Year: 2009
Asbestos-related disorders (ARDs): Influence of pleural plaques and pulmonary fibrosis due to asbestos exposure on lung function decline (LFD) Source: International Congress 2014 – ILDs 5 Year: 2014
Malignant pleural mesothelioma caused by environmental exposure to asbestos or erionite in Turkey: a retrospective analysis Source: Eur Respir J 2002; 20: Suppl. 38, 271s Year: 2002
Occupational and enviromental determinants of exposure to asbestos in malignant mesothelioma cases Source: Annual Congress 2011 - Mineral dusts Year: 2011
Non-asbestos related respiratory disease and lung function in an asbestos exposed cohort Source: Annual Congress 2010 - Mineral dusts and respiratory disease Year: 2010
Lung function in patients with benign asbestos related pleural disease Source: Eur Respir J 2003; 22: Suppl. 45, 185s Year: 2003
Decreasing incidence of pleural calcifications among metsovites with non-occupational asbestos exposure Source: Eur Respir J 2003; 22: Suppl. 45, 184s Year: 2003
Compensation of pleural mesothelioma in construction workers in France Source: International Congress 2017 – Shared exposures related to interstitial disease and airflow obstruction Year: 2017
Asbestos-related pleural disease including diffuse malignant mesothelioma Source: ISSN=1025-448x, ISBN=1-904097-25-1, page=189 Year: 2002
Factors associated to airway obstruction development in asbestos exposed workers in Navarra. Source: International Congress 2017 – Shared exposures related to interstitial disease and airflow obstruction Year: 2017
Asbestos exposure causes small airway obstruction among asbestosis patients Source: International Congress 2017 – Shared exposures related to interstitial disease and airflow obstruction Year: 2017