Focal adhesions control stretch-induced rho signaling and vascular permeability via paxillin – GEF-H1 functional complex

K. Birukov, G. Gawlak, Y. Tian (Chicago, United States Of America)

Source: International Congress 2014 – Experimental models in acute lung injury
Session: Experimental models in acute lung injury
Session type: Thematic Poster Session
Number: 3923
Disease area: Respiratory critical care

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
K. Birukov, G. Gawlak, Y. Tian (Chicago, United States Of America). Focal adhesions control stretch-induced rho signaling and vascular permeability via paxillin – GEF-H1 functional complex. Eur Respir J 2014; 44: Suppl. 58, 3923

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
LATE-BREAKING ABSTRACT: Protein tyrosine phosphatase (PTP)alpha promotes profibrotic responses in fibroblasts via Smad signaling
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014


Impact of Wnt ligand secretion on cellular phenotypes in pulmonary fibrosis
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014

Rac-specific nucleotide exchange factor Asef mediates lung endothelial barrier protection by hepatocyte growth factor
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014

Identification of novel proteins involved in beta-catenin dependent alveolar epithelial trans-differentiation
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014

GRP78 is a novel receptor initiating endothelial barrier protective response to oxidized phospholipids
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014


Gene expression changes of Wnt signalling components during alveolar epithelial transdifferentiation
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014

R-spondins induce canonical Wnt signaling in lung epithelial cells
Source: International Congress 2014 – Mechanisms of COPD: proteases and a whole lot more
Year: 2014

Involvement of JNK in TNFα driven remodelling
Source: International Congress 2015 – Cellular and molecular mechanisms of COPD and emphysema
Year: 2015

Ventilator-induced lung injury induces a positive signalling feedback loop between Nrf2 and amphiregulin
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014

Altered protein homeostasis in pulmonary fibrosis indicates a role for proteasomal activator 200
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014

Rapid activation of pulmonary endothelial cells during high stretch ventilation in vivo
Source: International Congress 2014 – Acute lung injury: hitting the barriers
Year: 2014



Antioxodants attenuates alveolar epithelial cell damage induced by a component of essential oils
Source: International Congress 2014 – Experimental models in acute lung injury
Year: 2014


Differential VEGF signalling in the lung
Source: Annual Congress 2013 –Growth factors at the crossroads of acute and chronic inflammation
Year: 2013


KCa3.1 mediates alphaSMA expression in human lung myofibroblast via the Smad2/3 and TGFbeta1 signalling pathway
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Disease-derived extracellular matrix scaffolds instruct the transdifferentiation and migration of lung fibroblasts
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014

Matriptase triggers pleiotropic functional responses in normal human lung fibroblasts (NHLF): Potential relevance in pathophysiology
Source: International Congress 2014 – Lung cell biology in injury and repair
Year: 2014

Polarization of alveolar macrophages is regulated by the immunoproteasome
Source: International Congress 2014 – Lung cell biology in injury and repair
Year: 2014


Evidence for a novel kit adhesion domain mediating human mast cell adhesion to structural airway cells
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Validation of the pitavastatin-induced angiomotin-like protein 1 that controls tight junction stability of lung microvascular endothelial cells via LKB1/AMPK activation
Source: International Congress 2015 – New insights into lung disease pathogenesis
Year: 2015

Fibroblast growth factor 9 (FGF9) modulates the phenotype of control and fibrotic human lung fibroblasts in vitro
Source: International Congress 2014 – New and old players in fibrotic lung disease
Year: 2014