Source: International Congress 2014 – ILDs 6
Disease area: Interstitial lung diseases

Abstract

Purpose:ILD patient's oxygenation should be asses at baseline and during follow-up evaluation. The increase in the red cell distribution width (RDW)is independent predictors of coronary thrombus burden and associated with increased mortality risk in patients with respiratory insufficiency.Our aim was to evaluate the correlation between hypoxemia and age, length of stay hospital,biochemical parameters, RDW, in-hospital mortality in patients with ILD.Method:A retrospective study was conducted on 184 patients who hospitalized for diffuse ILD in Pulmonary Department between 2010-2013.Results:The mean age of the patients was 62±13 and 51% were female. Patients were classified according to their partial oxygen pressure (PO₂) values; 7% of the patients were severe hypoxemia (< 40mmHg), while 20%were moderate hypoxemia (40-59mmHg), 18% were mild hypoxemia and 23%were non hypoxemic. In patients with severe or moderate hypoxemia white blood cells count was higher and pH values were lower than those who were not hypoxemics(p=0.004,p=0.005,p=0.001,p=0.003respectively). The RDW level had a mean value of 16.7±2.8 and RDW values were significantly higher in severe hypoxemic patients than the patients had no hypoxemia(p=0.009).No significant correlation was observed between PaO₂ levels of ILD patients and age, length of stay in hospital, biochemical parameters on admission and in-hospital mortality.Conclusion: Diffuse ILD seems to occur in elderly patients and hypoxemia can be observed during hospitalization. Although no correlation was observed between level of hypoxemia and length of stay in hospital or mortality,high RDW levels in severe hypoxemic patients may be secondary to right heart failure.

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Citations should be made in the following way:
E. Demirdogen Cetinoglu, A. Gorek Dilektasli, E. Uzaslan, A. Ursavas, E. Ege (Bursa, Turkey). Does hypoxemia increases risks in hospitalized patients with diffuse interstitial lung disease?. Eur Respir J 2014; 44: Suppl. 58, 3794

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