LATE-BREAKING ABSTRACT: Epidemiology of IPF in Italy S. Harari, F. Madotto, A. Caminati, S. Conti, G. Cesana (Via San Vittore 12, Milano, Via Bicocca degli Arcimboldi 8, Milano, Italy)
Source: International Congress 2014 – ILDs 6
Session: ILDs 6 Session type: Thematic Poster Session Number: 3781
Disease area: Interstitial lung diseasesAbstract IntroductionDespite its clinical relevance, IPF remains an uncommon disorder and few studies have focused on its epidemiology. Aim of the study is to investigate the prevalence and incidence of IPF in Lombardy, an Italian region with universal healthcare coverage for almost 10 million people, during 2005-2010.MethodsSubjects affected by IPF were identified using healthcare administrative databases of Lombardy Health System: vital status, hospitalizations and outpatient visits. We estimated annual standardized prevalence and incidence rates (100,000 person-years) adopting three different algorithms to identify IPF cases, called generic, broad and narrow case definition (GCD, BCD, NCD).ResultsThe mean annual prevalence rate was 35.5, 22.4 and 12.6 using respectively GCD, BCD and NCD. Prevalence increased with age and BCD and NCD showed a significantly higher rate in men. During the study period, we detected a positive trend of the annual prevalence rate. Annual incidence was estimated to 5.3 with GCD, 3.7 with BCD and 2.3 with NCD; like prevalence, incidence was higher among man than women and in elderly. Adopting GCD, we observed a decreasing trend in annual incidence rate (from 6.1 in 2005 to 4.5 in 2010), while the other case definitions detected a stable trend in annual incidence.ConclusionsIn Lombardy, IPF prevalence increased while incidence remained stable in the last years. It is therefore likely that disease duration has lengthened. The IPF prevalence and incidence identified in our population are lower than those reported by American studies and are consistent with those observed in other European studies.Rating:
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S. Harari, F. Madotto, A. Caminati, S. Conti, G. Cesana (Via San Vittore 12, Milano, Via Bicocca degli Arcimboldi 8, Milano, Italy). LATE-BREAKING ABSTRACT: Epidemiology of IPF in Italy. Eur Respir J 2014; 44: Suppl. 58, 3781
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