Source: Annual Congress 2002 - The development of allergic sensitization / asthma in children
Disease area: Airway diseases, Paediatric lung diseases

Abstract

The mites,especially of the family dermatophagoides pteronnyssinus are the main sources of the house dust allergens and an important etiological factor in allergic respiratory diseases.The objective of the research work is to pinpoint the significance of decreased exposition to HDM as a condition in preventing the asthma approaches.70 asthmatic patients aged 18-30,allergic to HDM have been divied in to 3 groups.The first group(N=22) was administrated with 400μg.Beclomethasone and impermeable cover was used.The second grouo(N=26) was administred with 400μg.Beclomethasone.Third group comprised(N=22) asthmatic who had been covered with impermeable cover and their environment was utterly freed from everything that had the slightest chance of consisting HDM(especially rugs,carpats..).FEV1 and symptoms score identified following a period 3 weeks,6 weeks and 12 weeks.The results showed statistically significant improvement to FEV1 with the first and third group.In addition asthmatics from the first and third group have shown significant improvement of the symptom score (P<0,01).We can conclude that the most important condition in the terapy of asthmatics sensitive to HDM is their through dislocation from their environment.In case completely contact with HDM can not be avoided further therapy with inhaled corticosteroides (Beclomethasone) is especially important.The relation between allergen exposure and asthma is very close.

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Citations should be made in the following way:
G. A. Breskovska, B. J. Caeva, G. J. Stevcevska, J. I. Stojkovic (Skopje, Macedonia). Influence of decreased allergen exposition in preventing bronchial asthma. Eur Respir J 2002; 20: Suppl. 38, 793

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