Source: Annual Congress 2002 - The development of allergic sensitization / asthma in children
Disease area: Airway diseases

Abstract

This study is to survey the main allergens in Guangzhou relative to episode of bronchial asthma, and to compare the difference between children and adults. The allergens causing asthma are very different all over the world due to the different geographic environments and climate. 102 stable asthmatic patients (48 children and 54 adults) were enrolled in the study. The standard allergen extracts from ALK-Abell of Denmark are used in skin prick test (SPT), total IgE (TIgE) is determined with CAP system. 12 allergens include Dermatophagoides farinae, Dermatophagoides pteronyssinus, house dust, mould and cat dander. The total positive rate is 83.3% in children, the positive rate of house dust mites is highest, that of Der. P and Der. F are all 79.2%. The house dust took second place, and it[scquote]s 72.9%. The total positive rate was 62.9% in adults, the positive rate of Der. P and Der. F are 59.3% and 62.9% respectively, the house dust took second place (40.7%). For animal dander, the dog dander was the most important allergen, and the cat dander took second place. For each allergen, there is significant difference between the total positive rate of children and that of adults, the positive rate of children is far higher than that of adults (p<0.01). The mean value of the total IgE of bronchial asthmatic patients is 506.14 KU/L, which is far higher than the normal people. Among these patients, the total IgE (671.74 KU/L) of the patients with positive SPT is different significantly from the total IgE (112.84 KU/L) of the patients with negative SPT (P<0.01). Our results showed that the main allergen for children and adults in Guangzhou area of China are house dust mites, and the positive rate of the asthmatic children to house dust mites is higher significantly than that of adults.

Rating:

Share or cite this content

Citations should be made in the following way:
Sun B., Lai K., Li J., Lou W., Zhong N. (Guangzhou, China). The survey of the common inhaled allergens in the bronchial asthmatic patients in Guangzhou area of China. Eur Respir J 2002; 20: Suppl. 38, 791

Member's Comments

No comment yet.

Related content which might interest you: A survey on the relationship between atopy and bronchial asthma among adolescents in the city of Guangzhou, China Source: Eur Respir J 2007; 30: Suppl. 51, 399s Year: 2007 The impact of age on allergen responsiveness in allergic rhinitics and asthmatics in the coastal area of southern Italy Source: Eur Respir J 2007; 30: Suppl. 51, 619s Year: 2007 Frequency of aeroallergen hypersensitivity in adult asthmatic patients in Trabzon, Turkey Source: Eur Respir J 2001; 18: Suppl. 33, 110s Year: 2001 Traffic exposure associated with allergic asthma and allergic rhinitis in adults. A cross-sectional study in southern Sweden Source: Annual Congress 2009 - Indoor and outdoor air pollution Year: 2009 Prevalence of asthma, rhinitis, conjunctivitis and skin sensitization to aeroallergens in schoolchildren of a traffic polluted area of Casablanca Source: Eur Respir J 2005; 26: Suppl. 49, 384s Year: 2005 Prevalence of sensitization to common aeroallergens among adolescents in Guangzhou, China Source: Annual Congress 2006 - Bronchial asthma and atopy – epidemiology, risk factors and risk assessment Year: 2006 Bronchial asthma prevalence in the pediatric population in an industrial area of the centre-south of Italy: preliminary results Source: Annual Congress 2009 - Air pollution and other exposures Year: 2009 Prevalence of sensitization to aeroallergens in patients with asthma and/or rhinitis in Thessaloniki Region - Northern Greece Source: Eur Respir J 2003; 22: Suppl. 45, 108s Year: 2003 The relationship of asthma symptoms and allergic sensitization to aero-allergens and food allergens in urban and rural schoolchildren Source: Annual Congress 2010 - New insights in the epidemiology of asthma Year: 2010 Prevalence of allergic asthma diagnosis in asthmatic patients visited by allergists and neumologists in Spain Source: Eur Respir J 2003; 22: Suppl. 45, 299s Year: 2003 Asthmatic symptoms and atopy in relation to microbial components in schools in Taiyuan, China Source: Eur Respir J 2006; 28: Suppl. 50, 698s Year: 2006 Increasing prevalence of bronchial hyperresponsiveness in three selected areas in East Germany Source: Eur Respir J 2001; 18: 451-458 Year: 2001 Hypersensitivity to cockroach allergen among children with bronchial asthma in Warsaw Source: Eur Respir J 2002; 20: Suppl. 38, 536s Year: 2002 Prevalence of asthma and allergic rhinitis in young adult citizens of Gdynia, Poland Source: Eur Respir J 2007; 30: Suppl. 51, 149s Year: 2007 Allergic sensitization profile of polysensitized asthmatic patients in Southern China using molecule-based IgE technique Source: International Congress 2019 – Asthma and allergies worldwide Year: 2019 Hypersensitivity to inhalant allergens among patients with asthma and allergic rhinitis in Saint Petersburg, Russia Source: Eur Respir J 2006; 28: Suppl. 50, 321s Year: 2006 Thunderstorm associated outbreak of bronchial asthma in Kuwait Source: Eur Respir J 2004; 24: Suppl. 48, 509s Year: 2004 Sensitization to indoor allergens in atopics and subjects with allergic asthma in R. Macedonia Source: Eur Respir J 2006; 28: Suppl. 50, 233s Year: 2006 Association between allergic rhinitis and hospital resource use among asthmatic children in Norway Source: Eur Respir J 2002; 20: Suppl. 38, 335s Year: 2002 Epidemiology of allergic rhinitis in asthmatic patients in Greece Source: Annual Congress 2011 - Respiratory epidemiology: comorbidity Year: 2011