Relation of month of birth and hypersensitivity to grass pollen in asthmatic children

M. R. Slavkovic-Jovanovic, S. Zivanovic, L. Saranac, Z. Zivkovic (Nis, Belgrade, Yugoslavia)

Source: Annual Congress 2002 - The development of allergic sensitization / asthma in children
Session: The development of allergic sensitization / asthma in children
Session type: Thematic Poster Session
Number: 780
Disease area: Airway diseases

Congress or journal article abstract

Abstract

Early infancy seems to be a period of particular susceptibility to sensitisation, as indicated by epidemiological and experimental studies. There is suggestion that pollen contact during the first six months of life increase the risk of pollen allergy for twenty years or more. Our aim was to analyse the relation between the month of birth and sensitisation to grass pollen in extrinsic asthmatic children.
We have tested group of 62 asthmatic children by skin prick test. The relative risk for development of hypersensitivity to grass pollen is calculated as: (number of positive cases born in that month / total number of patients born in that month) / (number of positive cases not born in that month / total number of patients not born in that month).
We find that relative risk of immediate hypersensitivity to grass pollen is dependent on the month of birth. When the relative risk of immediate hypersensitivity was plotted as a function of the month of birth a two-phase curve with maxim in Aplil - May and October – January was obtained for grass pollen allergy, and minimum for June – September period.
In addition to genetic factors, exposure in early childhood to grass pollen allergy is an important risk of the subsequent development allergy to grass pollen and later onset of asthma in children.


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M. R. Slavkovic-Jovanovic, S. Zivanovic, L. Saranac, Z. Zivkovic (Nis, Belgrade, Yugoslavia). Relation of month of birth and hypersensitivity to grass pollen in asthmatic children. Eur Respir J 2002; 20: Suppl. 38, 780

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