Source: International Congress 2014 – Longitudinal studies of respiratory disease
Disease area: Airway diseases

Abstract

Background: The prognosis of patients hospitalized with chronic obstructive pulmonary disease (COPD) is poor, both in the short and long terms, but the prognosis differs across countries and regions. Several risk factors for mortality have been identified. In many countries, smoking prevalence is now rapidly declining, standards of care for patients with COPD have improved, and decreasing hospitalization rates have been detected. In times of changing epidemiology regarding patients hospitalized for COPD, we wanted to examine the long-term mortality after hospitalization for COPD in Scandinavia.Methods: This work involved a cohort study of 716 patients hospitalized for COPD in 2005 at three Scandinavian hospitals. Long-term mortality was examined, and predictors for mortality were examined with univariate and multivariate analyses.Results: A total of 686 patients were discharged alive. 424 (62%) of the patients died during follow-up. Median survival time was 44.4 months (95% CI 39.2, 49.6). The 2-year mortality was 33%, and 4-year mortality was 52%. Age, previous hospitalizations for COPD, long-term oxygen therapy, heart failure, and thoracic malignancy were significant independent predictors of mortality in a multivariate analysis.Conclusion: Long-term mortality after hospitalization for COPD is high, and older patients with severe COPD, frequent previous hospitalizations, concurrent heart failure, or thoracic malignancy are at particular risk. Patients hospitalized for COPD should have thorough assessment of their treatment and comorbidities to optimize further care.

Rating:

Share or cite this content

Citations should be made in the following way:
E. D. Liaaen, A. H. Henriksen, N. Stenfors (Aalesund, Trondheim, Norway; Umeå, Sweden). Predictors of long-term mortality after hospitalization for COPD; A Scandinavian multicentre study. Eur Respir J 2014; 44: Suppl. 58, 2979

Member's Comments

No comment yet.

Related content which might interest you: One-year mortality in COPD patients after severe exacerbation Source: International Congress 2016 – Comorbidities and exacerbations in COPD Year: 2016 Incidence and outcomes of hospitalized for COPD exacerbations with and without pneumonia, 2006-2012: A nationwide cohort study Source: International Congress 2014 – Epidemiology, scores and outcomes of respiratory infections Year: 2014 COPD-specific co-morbidity test (COTE) for predicting mortality in COPD – Results of an European, multicenter study Source: International Congress 2014 – Markers Year: 2014 COPD exacerbation admissions: Analysis of demographics and mortality Source: Annual Congress 2013 –COPD treatment Year: 2013 Risk of cardiovascular events following COPD hospitalisation: Findings from the China Kadoorie Biobank cohort study Source: International Congress 2015 – COPD and lung function: risk factors and outcomes Year: 2015 Clinical characteristics of patients with frequent COPD exacerbations in a Swiss multicenter COPD cohort study (TOPDOCS) Source: International Congress 2016 – Targeting care, pulmonary rehabilitation, management, and self-management of COPD exacerbations in primary care Year: 2016 Stability of the frequent exacerbator – A Danish nationwide register-based study Source: International Congress 2016 – Management of asthma and COPD in primary care Year: 2016 Factors associated with COPD exacerbation frequency in a UK primary care cohort Source: Annual Congress 2013 –Risk factors for COPD and lung function decline Year: 2013 Comorbidities and COPD severity: The French Palomb cohort Source: International Congress 2016 – Comorbidities and exacerbations in COPD Year: 2016 Statin use and risk of exacerbations in individuals with COPD: The Copenhagen general population study Source: International Congress 2014 – New insights into the epidemiology of COPD Year: 2014 Effectiveness of self-treatment of exacerbations in COPD patients: Two-year follow-up of the COPE-II study Source: International Congress 2014 – Best abstracts in rehabilitation and chronic care (sponsored by MOTEK Medical) Year: 2014 Comorbidities, gender-differences and COPD severity: The French Palomb cohort Source: International Congress 2015 – Risk factors and co-morbidities in asthma and COPD Year: 2015 Cardiovascular risk assessment in COPD patients with severe exacerbation Source: International Congress 2016 – Comorbidities and exacerbations in COPD Year: 2016 The prevalence of co-morbidities and exacerbations in COPD patients in Slovenia Source: International Congress 2015 – Risk factors and co-morbidities in asthma and COPD Year: 2015 15-Year mortality after hospitalization for COPD in a Dutch teaching hospital: Preliminary data from the MORTCOP cohort Source: International Congress 2016 – Prevalence, prognosis, and risk factors of COPD Year: 2016 Corerelation of COPD exacerbation with comorbidities, Lung function and mortality within a single-practice primary-care cohort in the UK Source: International Congress 2019 – Multimorbidity in airway diseases and appropriate inhaled corticosteroid use in COPD Year: 2019 Risk factors associated to COPD worsening in Italian general practices: The 12 month COMODHES follow-up study Source: International Congress 2014 – Prevalence of COPD and mortality from COPD Year: 2014 Efficacy and safety of erdosteine in COPD: Results of a 12-month prospective, multinational study Source: International Congress 2015 – New data on established treatments for COPD Year: 2015 Co-morbidities of adult smokers at risk of COPD evaluated in a 6-year prospective study Source: International Congress 2015 – COPD: notable points Year: 2015 Multinational, database cohort study to study mortality and risk factors of mortality in patients with asthma Source: International Congress 2016 – Asthma and allergy in infancy: from risk factors to mortality Year: 2016