Source: International Congress 2014 – Clinical management of interstitial lung diseases and vasculitis
Disease area: Interstitial lung diseases, Pulmonary vascular diseases

Abstract

Aim: to analyze causes of PE and to describe of clinical, radiological and hemodynamic characteristics of PE in PS pts.Matherial and methods. We studied 27 cases PE in pts PS Patients were subjected to clinical and radiological (CT, perfusion scinthiography, HRCT, CT-angiography, and SPECT with ^99m) researches, echodopplercardiography (EDC).Results. The main PE cause was deep venous thrombosis in 17 pts (0.63). All pts had predisposing factors for venous thromboembolism, including trombophilia. PE was found in 2 pts with morphologically confirmed cardiac sarcoidosis with right heart failure. Clinical symptoms were: dispnoea (0.88), haemoptysis (0.70), chest pain (0.62), cough (0.37), tachypnoea (0.70), tachycardia (0.48). Comparison EDC data of pts and healthy volunteers revealed: increasing of systolic pulmonary artery pressure (29.74±2.06 mm Hg, p<0.01 vs 23.7 ± 1.0 mm Hg in control group). , right ventricular wall diastolic thickness (0.39±0.06 cm, p<0.05 vs 0.26±0.02 cm), right ventricular diastolic dimension (2.78±0.13 cm, p<0.05 vs 2.51± 0.08 cm) and decreasing of fraction right ventricular wall systolic thickness (0.44±0.07 vs 0.59±0.04), E/A right ventricular diastolic filling ratio (1.28±0.05 vs 1.64±0.05), E/A left ventricular diastolic filling ratio (1.17±0.21 vs 1.69±0.04). The combination of CT-angiography and SPECT revealed additionally in 10 cases signs of PE, including thrombosis «in situ» in 3 PS pts of 4 stage.Conclusions: 1. The modern methods investigations (EDC, CT-angiography, SPECT) allow detection PE in PS patients, including thrombosis «in situ». 2. The main cause of PE is DVT with the presence of predisposing factors for venous thromboembolism, including markers of trombophilia.

Rating:

Share or cite this content

Citations should be made in the following way:
O. Baranova, V. Perlei, A. Gichkin, V. Zolotnitskaya, A. Speranskaya (Saint-Petersburg, Russian Federation). Pulmonary embolism (PE) in patients with pulmonary sarcoidosis (PS). Eur Respir J 2014; 44: Suppl. 58, 4508

Member's Comments

No comment yet.

Related content which might interest you: Difficulties of diagnosis of pulmonary embolism (PE) in patients with lymphangioleiomyomatosis (LAM) Source: Annual Congress 2013 –Novel biomarkers and old parameters in clinical management of lung diseases Year: 2013 Pulmonary embolism (PE) in amiodarone-induced pulmonary toxicity (AILT) Source: International Congress 2016 – Orphan diseases II Year: 2016 CPFE (combined pulmonary fibrosis and emphysema): A case series Source: International Congress 2014 – Clinical management of interstitial lung diseases and vasculitis Year: 2014 Bilateral chylothorax in a patient with chronic central vein thrombosis and chronic thromboembolic pulmonary hypertension (CTEPH) Source: International Congress 2014 – Clinical management of lung diseases: from bronchi to pleura Year: 2014 Pulmonary embolism in COPD patients Source: Annual Congress 2013 –COPD treatment and others Year: 2013 Incidence of Chronic Thromboembolic Pulmonary Hypertension (CTEPH) at six months of a Pulmonary Embolism (PE). OSIRIS Study Source: International Congress 2017 – Prognostic factors and outcomes in pulmonary embolism Year: 2017 Integration of the level of D-dimer (D-d) with Wells criteria to improve the prediction of pulmonary embolism (PE) before CT angiography of the lung (CTAL) Source: International Congress 2014 – Acute pulmonary embolism Year: 2014 Prevalence of relapses and chronic thromboembolic pulmonary hypertension (CTEPH) in patients with pulmonary embolism (PE) Source: International Congress 2016 – Pulmonary hypertension: exercise, haemodynamics, and physiology Year: 2016 The management and follow-up of pulmonary embolism (PE) at a district general hospital: Are we missing CTEPH? Source: Annual Congress 2013 –Pulmonary circulation: chronic thromboembolic pulmonary hypertension, imaging and biomarkers Year: 2013 From CTPA-proven pulmonary embolism to patients clinical characteristics Source: Annual Congress 2013 –Pulmonary circulation: acute pulmonary tromboembolism Year: 2013 Clinical assessment of pulmonary embolism rule-out criteria (PERC). Retrospective study (2006-2015) Source: International Congress 2016 – Pulmonary hypertension in lung disease Year: 2016 Pulmonary thromboembolism (PE) in patients with interstitial lung diseases (ILD) Source: International Congress 2016 – Epidemiological and clinical data regarding the modern management of chronic lung diseases Year: 2016 Stress-Doppler-Echocardiography for early detection of systemic sclerosis associated pulmonary arterial hypertension Source: International Congress 2014 – Modern approach and old dilemmas in lung diseases Year: 2014 Late Breaking Abstract - Frequency Pulmonary embolism (PE) in patients with an acute Exacerbation of chronic obstructive Pulmonary disease (COPD). PEP prospective trial. Source: International Congress 2019 – Pulmonary embolism: from diagnosis to prognosis and treatment Year: 2019 Clinical significance of C reactive protein and MASTORA score in pulmonary embolism Source: International Congress 2014 – Clinical problems in acute and chronic lung diseases Year: 2014 Evaluation of a novel clinic for management of Chronic Thromboembolic Pulmonary Disease (CTED) and associated Pulmonary Hypertension (CTEPH). Source: International Congress 2017 – PAH and CTEPH Year: 2017 30 years experience of plasmapheresis using in complex treatment of pulmonary sarcoidosis (PS) Source: International Congress 2014 – Clinical management of interstitial lung diseases and vasculitis Year: 2014 The incidence of chronic thromboembolic pulmonary hypertension in asympthomatic pulmonary embolism patients Source: International Congress 2014 – Chronic thromboembolic pulmonary hypertension Year: 2014 Early screening for reperfusionand CTEPH after acute pulmonary embolism – Early screening for reperfusion and CTEPH after acutepulmonary embolism Source: International Congress 2014 – Pulmonary hypertension: clinical management Year: 2014 Long-term screening for pulmonary hypertension after pulmonary embolism Source: International Congress 2014 – Chronic thromboembolic pulmonary hypertension Year: 2014