Source: International Congress 2014 – Clinical allergy
Disease area: Airway diseases

Abstract

Objectives: We investigated the distribution of common allergens in allergic patients in Guangzhou, southern China.Methods: 7,085 patients with allergic symptoms were examined for serum Total IgE (TIgE) sIgE to 15 common allergens in this region, based on the protocol of reversed enzyme allergosorbent test.Results: 3,758 (53.04%) of the subjects tested positive for TIgE and 4640 (65.49%) for sIgE to at least one of the 15 common allergens. There was no statistical difference in the overall rate of positive sIgE detection between males (3081/4602, 66.95%) and females (1674/2483, 67.42%). Der pteronyssinus and Der farinae were the most common aeroallergens, while eggs and cow's milk the most common food allergens, responsible for higher positive rates of sIgE responses. By age-group analysis, we noted several peaks of sensitization to the certain allergens: Der pteronyssinus, Der farinae, and Blomia tropicalis at age between 9 and 18;cow's milk before age 3; eggs at age between 3 and 6. Along with older age, there was an ascending tendency in the overall positive rate of sIgE response to house dust mites among subjects who tested positive for sIgE to eggs or cow's milk.Conclusions: Such a sequence of events may be a result of allergy march. Knowledge on the prevalence of allergen sensitization in different age groups would help early diagnosis and intervention of allergic diseases in this large geographical region.

Rating:

Share or cite this content

Citations should be made in the following way:
B. Sun, P. Zheng (Guangzhou, China). Prevalence of allergen sensitization among patients with allergic diseases in Guangzhou, Southern China: A six-year observational study. Eur Respir J 2014; 44: Suppl. 58, 4040

Member's Comments

No comment yet.

Related content which might interest you: Modern allergy diagnostics in China: The past and present Source: International Congress 2014 – Clinical allergy Year: 2014 Radioallergosorbant testing – A Southern Saskatchewan experience Source: Annual Congress 2013 –Genetics and mechanisms of, and tests for, allergy Year: 2013 Cohort study of patients with asthma and immunodeficiency Source: International Congress 2014 – Asthma: clinical problems Year: 2014 Sensitization to airborne allergens among adults and its impact on allergic symptoms: A population survey in northern Vietnam Source: International Congress 2014 – Epidemiology of asthma Year: 2014 Monitoring the profile of mould sensitization in children and adults in Volga region Source: International Congress 2014 – Clinical allergy Year: 2014 Allergen microarray detection of specific IgE in southern Chinese pollen allergy patients Source: International Congress 2014 – Paediatric asthma: epidemiology and risk factors Year: 2014 The results of the immunomorphological study of the placenta in women with asthma Source: International Congress 2014 – Allergy and asthma: novel findings based on human cell biology Year: 2014 Aspergillus skin hypersensitivity in patients of COPD Source: International Congress 2014 – Clinical allergy Year: 2014 Fungal sensitization in patients with moderate and severe asthma Source: International Congress 2014 – Clinical allergy Year: 2014 Changes in pollen sensitization over last twenty years in Tunisia Source: International Congress 2015 – Novel mechanisms and treatments in allergy and asthma Year: 2015 Subcutaneous allergen specific immunotherapy and immunological response in patients with bronchial asthma and allergic rhinitis in India Source: International Congress 2014 – Intervening in allergic asthma Year: 2014 Atopy and allergic disease in rural Poland before and after accession to the European Union Source: Annual Congress 2013 –Environment and lifestyle: associations with respiratory disease Year: 2013 Sensitization to blomia tropicalis, and to others aeroallergens: Relation to asthma and rhinitis in French Caribbean Island Source: Annual Congress 2013 –Epidemiology of asthma Year: 2013 Autoimmune disorders in allergen immunotherapy, allergic rhinitis, and non-allergic patients Source: International Congress 2014 – Intervening in allergic asthma Year: 2014 Skin prick test versus specific IgE – A comparative study in patients with bronchial asthma and allergic rhinitis in India Source: International Congress 2014 – Clinical allergy Year: 2014 Patterns of clinical use of omalizumab in Spain: A 5-year "real-life" study Source: International Congress 2014 – Intervening in allergic asthma Year: 2014 Prevalence and comorbidities of bronchial asthma in Germany – A population based study of 185.999 patient cases in Saarland Source: International Congress 2014 – Asthma: clinical problems Year: 2014 Lung function response to omalizumab in severe allergic asthma patients in UK clinical practice: APEX II study Source: International Congress 2014 – Intervening in allergic asthma Year: 2014 A population-based study of animal component sensitization, asthma and rhinitis in school children Source: International Congress 2015 – Prevalence of respiratory disease Year: 2015 Regional differences in sensitization to Ambrosia in Croatian children Source: International Congress 2014 – Paediatric asthma: epidemiology and risk factors Year: 2014