Source: International Congress 2014 – COPD: points to ponder
Disease area: Airway diseases

Abstract

Objective: to study pulmonary diffusing capacity (DL_CO) and frequency of osteoporosis in patients with chronic obstructive pulmonary disease (COPD).Material and Methods: 125 patients with chronic obstructive pulmonary disease (COPD) were observed. The investigated group was made by the men having the long experience of smoking. Smoker index was 240. The average age was 61.4 ± 6.4 years. The patients received basic therapy system glucocorticoids have been excluded from the research. Research of function of external breath was studied with multimodular installation of type «Master-Lab/Jaeger». Pulmonary diffusing capacity (DL_CO) was studied. Research of bone mineral density (BMD) of a bone fabric was studied with the method x-ray absorbtiometry with the densitometer « Lunar DPX-NT».Results: Indicators of pulmonary diffusing capacity (DL_CO) in patients with COPD were highest at the 2 stage of COPD and were 70,6 ± 20,3. The level of DL_CO in patients with 3 stage COPD was 53,9 ± 17,6 (p <0.0001). The lowest levels of DL_CO were detected in patients with COPD 4 stage 35,9 ± 15,4 (p <0.0001). DL_CO/VA in patients 2 stage COPD was 78,1±24,9, DL_CO/VA in patients with 3 stage COPD was 62,4 ± 17,01, DL_CO/VA in patients with 4 stage COPD was 52,8± 29,4. Frequency of osteoporosis of femoral neck according densitometry in patients with DL_CO <40% was 46.15%. Frequency of osteoporosis of femoral neck in patients with DL_CO 40-60% was 19.35%. The correlation coefficient between DL_CO / VA and BMD of hip was 0,59 (p< 0,01).Conclusions: increased frequency of osteoporosis in patients with COPD is associated with decrease of pulmonary diffusing capacity.

Rating:

Share or cite this content

Citations should be made in the following way:
E. Kochetova (Petrozavodsk, Russian Federation). Frequency of osteoporosis and pulmonary diffusing capacity in patients with chronic obstructive pulmonary disease (COPD). Eur Respir J 2014; 44: Suppl. 58, 3639

Member's Comments

No comment yet.

Related content which might interest you: Pulmonary diffusing capacity and the risk of fractures in patients with chronic obstructive pulmonary disease (COPD) Source: International Congress 2014 – COPD markers Year: 2014 Detection of chronic obstructive pulmonary disease (COPD) in patients with cardio-vascular system pathology Source: Annual Congress 2013 –COPD treatment and others Year: 2013 Some gender features of the chronic obstructive pulmonary disease Source: Annual Congress 2013 –COPD treatment Year: 2013 Early phenotypes of chronic obstructive pulmonary disease (COPD) Source: International Congress 2015 – Different data in COPD Year: 2015 Prevalence of co-morbidities with chronic obstructive pulmonary disease (COPD) in a primary care cohort Source: International Congress 2014 – Clinical presentations Year: 2014 To study the severity of lung hyperinflation and bone mineral density in patients with chronic obstructive pulmonary disease (COPD) Source: Annual Congress 2013 –COPD mechanisms Year: 2013 Clinical Impact of Gensini score in chronic obstructive pulmonary disease (COPD) Source: International Congress 2016 – Monitoring comorbidities Year: 2016 Factors associated with exacerbation in a general practitioners’-based Swiss chronic obstructive pulmonary disease (COPD) cohort Source: Annual Congress 2013 –The best posters in chronic care Year: 2013 Nutritional status in chronic obstructive pulmonary disease Source: International Congress 2014 – Comorbidities Year: 2014 Variability in clinical practice for chronic obstructive pulmonary disease in outpatient clinics Source: International Congress 2015 – Different data in COPD Year: 2015 Effects of pulmonary rehabilitation on exacerbation number and severity in people with chronic obstructive pulmonary disease (COPD) Source: International Congress 2016 – Hospitalisation and comorbidities in chronic lung diseases Year: 2016 Prediction of chronic renal failure in patients with chronic obstructive pulmonary disease Source: International Congress 2014 – COPD: points to ponder Year: 2014 Prevalence of vitamin D deficiency in patients with chronic obstructive pulmonary disease Source: International Congress 2015 – Non-exhaled biomarkers in the assessment of airways disease Year: 2015 Relationship between dyspnea and depression in the elderly patients with chronic obstructive pulmonary disease Source: International Congress 2014 – COPD: points to ponder Year: 2014 LATE-BREAKING ABSTRACT: Evaluation of symptoms and risk on stable chronic obstructive pulmonary disease patients with radiographic bronchiectasis Source: International Congress 2014 – Predictors Year: 2014 Prevalence of metabolic syndrome in patients with chronic obstructive pulmonary disease Source: International Congress 2016 – Hospitalisation and comorbidities in chronic lung diseases Year: 2016 Pulmonary hypertension (PH) in chronic obstructive pulmonary disease (COPD): Preliminary data of a longitudinal survey Source: International Congress 2014 – Clinical presentations Year: 2014 The systemic inflammation and factors of coagulation in patients with chronic obstructive pulmonary disease (COPD) Source: International Congress 2014 – COPD markers Year: 2014 Are re-admissions with acute exacerbation of chronic obstructive pulmonary disease coded correctly? Source: International Congress 2014 – COPD exacerbations Year: 2014 The serum level of surfactantproteind in patients with chronic obstructive pulmonary disease, depending on the nutrtional status Source: International Congress 2015 – Notable abstracts in exacerbations, mechanisms and biomarkers in COPD Year: 2015