Comparison of current therapies against endothelin-induced growth in pulmonary smooth arterial muscle cells (PASMCs) derived from patients with pulmonary arterial hypertension

J. Patel, D. Abraham, A. Nelson, A. Silverstein, L. Clapp (London, United Kingdom; Durham, United States Of America)

Source: International Congress 2014 – Pulmonary hypertension: novel targets and drugs
Session: Pulmonary hypertension: novel targets and drugs
Session type: Thematic Poster Session
Number: 2355
Disease area: Pulmonary vascular diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
J. Patel, D. Abraham, A. Nelson, A. Silverstein, L. Clapp (London, United Kingdom; Durham, United States Of America). Comparison of current therapies against endothelin-induced growth in pulmonary smooth arterial muscle cells (PASMCs) derived from patients with pulmonary arterial hypertension. Eur Respir J 2014; 44: Suppl. 58, 2355

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Smooth muscle microparticles as novel biomarkers of vascular remodelling and inflammation in pulmonary arterial hypertension
Source: International Congress 2014 – Pulmonary hypertension: novel targets and drugs
Year: 2014

Muscle function and physical activity in patients with idiopathic pulmonary arterial hypertension (IPAH)
Source: International Congress 2014 – Pulmonary hypertension: clinical management
Year: 2014

Obligatory role of MEK/ERK/RSK90 in the mitogenic responses of human pulmonary artery smooth muscle cells
Source: International Congress 2014 – Pulmonary hypertension: pathobiology
Year: 2014

Endothelial microparticles and progenitor cells in pulmonary arterial hypertension
Source: International Congress 2014 – Pulmonary hypertension: pathobiology
Year: 2014

Increased Cyr61 in pulmonary arterial hypertension involving in proliferation of pulmonary arterial smooth muscle cells
Source: International Congress 2016 – Pulmonary hypertension and pulmonary embolism: from the bench to the bedside
Year: 2016


Sildenafil improves heart rate variability, pulmonary hemodynamics and functional status in pulmonary arterial hypertension
Source: International Congress 2014 – Pulmonary hypertension: right ventricle and basic physiology
Year: 2014

Insulin-like growth factor-1 contributes to the pulmonary artery smooth muscle cell proliferation in pulmonary arterial hypertension
Source: International Congress 2014 – Pulmonary hypertension: pathobiology
Year: 2014

Characterization of circulating CD133+ progenitor cells in pulmonary arterial hypertension
Source: International Congress 2014 – Pathobiology of pulmonary hypertension
Year: 2014

LSC 2014 abstract - Combined effects of inflammatory mediators and BMPR2 mutation on pulmonary arterial cell function in a pulmonary arterial hypertension
Source: International Congress 2014 – Pulmonary hypertension: pathobiology
Year: 2014

Nuclear IL-33 arguments ST2 receptor expression in pulmonary arterial endothelial cells: Implication in the pathogenesis and progression of pulmonary arterial hypertension
Source: International Congress 2014 – Pulmonary hypertension: pathobiology
Year: 2014

Specific pulmonary arterial hypertension therapy in COPD patients with severe pulmonary hypertension
Source: International Congress 2014 – Pulmonary hypertension in lung disease
Year: 2014


Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension
Source: International Congress 2014 – Chronic thromboembolic pulmonary hypertension
Year: 2014

Skeletal muscle impairment and proteomic profil in human pulmonary arterial hypertension
Source: International Congress 2014 – Pathobiology of pulmonary hypertension
Year: 2014

mir-126 contribute to angiogenesis defect in pulmonary arterial hypertension right ventricle failure
Source: International Congress 2014 – Pulmonary hypertension: right ventricle and basic physiology
Year: 2014

Peripheral arterial stiffness and endothelial dysfunction in pulmonary arterial hypertension
Source: International Congress 2015 – Pulmonary hypertension: the right ventricle and its load
Year: 2015

The role of anion exchanger on pulmonary vascular response to sustained alveolar hypoxia in the isolated perfused rabbit lung
Source: International Congress 2014 – Pulmonary hypertension in lung disease
Year: 2014


Sildenafil decreases the contractile response to serotonin (5HT) in pulmonary arteries from patients with idiopathic pulmonary fibrosis (IPF) and pulmonary hypertension (PH)
Source: International Congress 2014 – Pulmonary hypertension in lung disease
Year: 2014


miR-126; link between angiogenesis and exercise intolerance in pulmonary arterial hypertension
Source: International Congress 2014 – Pulmonary hypertension: pathobiology
Year: 2014

Cerebral tissue oxygenation in arterial and thromboembolic pulmonary hypertension
Source: International Congress 2014 – Pulmonary hypertension: right ventricle and basic physiology
Year: 2014


Role of NMDA receptors in vascular remodelling associated to pulmonary hypertension
Source: International Congress 2014 – Pulmonary hypertension: pathobiology
Year: 2014