Dissociation between clinical trial inclusion and exclusion criteria for trials in severe asthma and the reality of the patient population

T. Brown, H. Rupani, C. Barber, S. Elliot, K. Gove, L. Lau, L. Hewitt, E. Ray, E. Aitken, S. Kerley, R. Kurukulaaratchy, C. Grainge, R. Djukanovic, A. Chauhan, P. Howarth (Portsmouth, Southampton, United Kingdom)

Source: International Congress 2014 – Novel approaches and evidence for drug development in respiratory diseases
Session: Novel approaches and evidence for drug development in respiratory diseases
Session type: Poster Discussion
Number: 3326
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
T. Brown, H. Rupani, C. Barber, S. Elliot, K. Gove, L. Lau, L. Hewitt, E. Ray, E. Aitken, S. Kerley, R. Kurukulaaratchy, C. Grainge, R. Djukanovic, A. Chauhan, P. Howarth (Portsmouth, Southampton, United Kingdom). Dissociation between clinical trial inclusion and exclusion criteria for trials in severe asthma and the reality of the patient population. Eur Respir J 2014; 44: Suppl. 58, 3326

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
What are common COPD symptoms in a real-life setting? The German DACCORD registry
Source: International Congress 2014 – COPD markers
Year: 2014

P-PiXel: A ’real-life’ evaluation of omalizumab use in asthmatic patients
Source: International Congress 2016 – Asthma management
Year: 2016

Pharmacokinetics of tiotropium in asthma patients from three paediatric clinical trials
Source: International Congress 2016 – Paediatric asthma: lessons learned from studies with large sample sizes and multi-centre drug studies
Year: 2016


A randomized phase 3 study of the efficacy and safety of reslizumab in subjects with asthma with elevated eosinophils
Source: International Congress 2014 – Clinical trials of drugs and biomarkers for respiratory diseases
Year: 2014

Efficacy of omalizumab in Polish real-world patients
Source: International Congress 2016 – Asthma management
Year: 2016


A randomized phase 3 study of reslizumab efficacy in relation to blood eosinophil levels in patients with moderate to severe asthma
Source: International Congress 2014 – Clinical trials of drugs for respiratory diseases
Year: 2014

Experience with omalizumab in patients with moderate and severe asthma
Source: International Congress 2014 – New clinical evidence for asthma and COPD treatments
Year: 2014


LATE-BREAKING ABSTRACT: Effectiveness of individualized self management support for children with asthma in Dutch outpatient clinics, preliminary results of a randomized controlled trial.
Source: International Congress 2014 – Paediatric asthma: pharmacological and non-pharmacological management
Year: 2014

Clinical profile and treatment of elderly patients hospitalized for acute exacerbation of asthma . A comparative study
Source: International Congress 2014 – Asthma: clinical problems
Year: 2014


International perspectives on severe asthma: Current and future challenges in patient care
Source: International Congress 2016 – Asthma points to ponder
Year: 2016

Distribution and outcomes of the new Spanish phenotype-based guideline for COPD
Source: International Congress 2014 – COPD exacerbations
Year: 2014

Characteristics of the adult corticosteroid-dependent severe asthma in UBIOPRED consortium
Source: International Congress 2014 – Novel targets and drugs for asthma and COPD
Year: 2014

Global evaluation of treatment effectiveness (GETE) is an accurate predictor of response to omalizumab in patients with severe allergic asthma: A pooled analysis
Source: International Congress 2014 – Intervening in allergic asthma
Year: 2014


Ketamine versus aminophylline for status asthmatic in children: A randomized, controlled trial
Source: International Congress 2014 – Lung disease in neonates and beyond
Year: 2014

A national database study of the effectiveness of switching real-life asthma patients to fostair
Source: International Congress 2015 – New data on established treatments for asthma, COPD and bronchiectasis
Year: 2015


Safety and tolerability of acute dosing of beta-blockers in asthma
Source: Annual Congress 2013 –Asthma and COPD management: novel clinical findings
Year: 2013

Clinical trials for elderly patients with multiple diseases (CHROMED): A pilot study
Source: International Congress 2014 – The assessment of comorbidities
Year: 2014

Analysis of comorbidities and treatment patterns by GOLD 2013 criteria: Pooled data from Phase III aclidinium bromide studies
Source: International Congress 2014 – Asthma and COPD management
Year: 2014

Abediterol in stable asthma:efficacy, safety and tolerability results from a Phase II, randomised, crossover study
Source: International Congress 2014 – Asthma and COPD management
Year: 2014

Clinical, functional and laboratory assessment of treatment efficacy in COPD patients
Source: International Congress 2014 – Predictors
Year: 2014