Source: Annual Congress 2002 - Treatment and outcome of acute respiratory failure in chronic disease

Abstract

In a period of 14 month 70 patients were admitted to our ICU due to ARF. Among them: bronchial asthma (BA) – 25 /male – 8, female – 17, mean age – 50/; COPD – 14 /all male, mean age – 61/; pneumonia – 10 /male – 6, female – 4, mean age – 48/; others – 21 /male – 10, female – 11, mean age – 42/. One half of the patients admitted to ICU due to BA exacerbation were considered to experience status asthmaticus. Pneumonia was bilateral in 6 patients (60%), destructive in 5 (50%), SIRS accompanied in 4 (40%), and multiorgan failure complicated in 2 (20%). The others group embraced 5 pulmonary embolies, 4 Mendelson's syndromes, 5 interstitial lung diseases, 3 decompensated tracheal stenosis, 3 thoracic deformations, 1 primary pulmonary hypertension. Estimated parameters were: quota of mechanically ventilation (MV) required, duration of MV, mean ICU stay, total hospital stay after ICU discharge, mortality rate, survivors and deceased mean ages. Results: see table. Conclusions: The best results were achieved in BA treatment, corresponding to reversible bronchoobstruction as main pathogenic factor. Less favorable results with COPD, correlating with age. The complete female absence in COPD group was noted. The worse in pneumonia, which may be caused by often SIRS crossing, multiorgan failure.

Group, total	MV, amount	MV duration, days	ICU stay,days	Days of hospital stay after discharge from ICU	Mortality	Survivors mean age	Deceased mean age
BA - 25	9 (36%)	4.4	2.2	9.1	2 (8%)	48.6	67.5
COPD - 14	8 (44.4%)	8.5	8.5	29.0	5 (36%)	58.1	69.0
Pneumonia - 10	6 (60%)	14.0	12.7	18.2	5 (50%)	47.1	49.3
Others - 21	12 (24%)	13.1	10.9	12.8	3 (6%)	46.8	66.3

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Citations should be made in the following way:
N. E. Okouneva, P. K. Yablonsky, A. V. Nefedov (St-Petersburg, Russia). Acute respiratory failure (ARF): peculiarities of the course corresponding to the nature. Eur Respir J 2002; 20: Suppl. 38, 607

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