Development of a myeloid cell-binding adenovirus for the potential gene therapy of alpha-1 anti-trypsin deficiency

M. Buggio, C. Towe, D. T. Curiel (St. Louis, United States Of America)

Source: International Congress 2014 – Translational studies in COPD
Session: Translational studies in COPD
Session type: Thematic Poster Session
Number: 852
Disease area: Airway diseases

Congress or journal article abstract

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Buggio, C. Towe, D. T. Curiel (St. Louis, United States Of America). Development of a myeloid cell-binding adenovirus for the potential gene therapy of alpha-1 anti-trypsin deficiency. Eur Respir J 2014; 44: Suppl. 58, 852

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Comprehensive characterization of the lung proteasome
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Validating SIK as a novel COPD target using four different human systems
Source: International Congress 2014 – Translational studies in COPD
Year: 2014


Different roles for PI3Kgamma and δ in asthma
Source: International Congress 2014 – Animal models: asthma, COPD and beyond
Year: 2014

Modulation of neutrophil functionalities by indacaterol and their relevance for chronic lung diseases
Source: International Congress 2014 – Translational studies in COPD
Year: 2014

Complex extracellular matrix modulates neutrophil migration in vitro
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Expression of CX3CL1 and CX3CR1 in human asthmatic lung in relation to cell survival
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Investigation of the mechanism(s) of oxygen-induced ciliated epithelial loss in bovine bronchus tissue
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

Transcriptional analysis of the human BPIFA1/SPLUNC1 gene
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013

Crosstalk between epithelium and fibroblasts; implications for COPD
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Protein tyrosine phosphatase PTPRR regulates PP2A in mononuclear cells
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014


Adaptation of lung epithelial cells subjected to chronic cyclic strain
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

A potential role for endothelial adhesion molecules and cytokines in chemotherapy-induced lung fibrosis
Source: International Congress 2014 – Cell biology 2014
Year: 2014


Omalizumab prevents smooth muscle cell growth induced by asthmatic serum
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014


Surface expression of CTLA-4 on CD4/CD25high cells in lung cancer
Source: International Congress 2014 – Basic and translational research in lung cancer and non-neoplastic pulmonary diseases
Year: 2014


Evidence for a novel kit adhesion domain mediating human mast cell adhesion to structural airway cells
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Modulation of PD-1 and PD-L1 expression in response to acute viral infection of human lung tissue
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Cell type specific accessibility of C5aR2 on human blood cells of myeloid origin
Source: International Congress 2016 – Immune responses in the lung
Year: 2016

Proteomic investigation of pulmonary sarcoidosis
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014


Molecular mechanisms of pirfenidone activity in human lung fibroblasts
Source: International Congress 2014 – Basic and translational research in lung cancer and non-neoplastic pulmonary diseases
Year: 2014


Role of TRPC6 channel in eosinophil function
Source: Annual Congress 2013 –Cell biology and murine models of asthma and inflammation
Year: 2013