Validating SIK as a novel COPD target using four different human systems

M. Göransson, U. Hedström, B. Fuchs (Gothenburg, Sweden)

Source: International Congress 2014 – Translational studies in COPD
Session: Translational studies in COPD
Session type: Thematic Poster Session
Number: 834
Disease area: Airway diseases

Congress or journal article abstractE-poster

Rating: 0
You must login to grade this presentation.

Share or cite this content

Citations should be made in the following way:
M. Göransson, U. Hedström, B. Fuchs (Gothenburg, Sweden). Validating SIK as a novel COPD target using four different human systems. Eur Respir J 2014; 44: Suppl. 58, 834

You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.

Member's Comments

No comment yet.
You must Login to comment this presentation.


Related content which might interest you:
Different roles for PI3Kgamma and δ in asthma
Source: International Congress 2014 – Animal models: asthma, COPD and beyond
Year: 2014

Comprehensive characterization of the lung proteasome
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Crosstalk between epithelium and fibroblasts; implications for COPD
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Modulation of neutrophil functionalities by indacaterol and their relevance for chronic lung diseases
Source: International Congress 2014 – Translational studies in COPD
Year: 2014

Development of a myeloid cell-binding adenovirus for the potential gene therapy of alpha-1 anti-trypsin deficiency
Source: International Congress 2014 – Translational studies in COPD
Year: 2014

Complex extracellular matrix modulates neutrophil migration in vitro
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Multi-analyte profiling of inflammatory markers in COPD sputum
Source: International Congress 2014 – Translational studies in COPD
Year: 2014

Reconstituted human airway epithelium 3D-model to assess the impact of air pollutants on the inflammatory response
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

The effects of INTS12 knockdown on processing of snRNAs
Source: International Congress 2014 – Novel epigenetic regulators for targeting via nanomedicine
Year: 2014



Adaptation of lung epithelial cells subjected to chronic cyclic strain
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

Protein tyrosine phosphatase PTPRR regulates PP2A in mononuclear cells
Source: International Congress 2014 – New insights into monocyte and macrophage biology
Year: 2014


The expression of the negative regulator of gene transcription SOCS3 as the crucial marker in the asthma pathogenesis
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Airway smooth muscle myosin phosphatase target subunit 1 phosphorylation in allergic asthma model
Source: International Congress 2014 – Animal models: asthma, COPD and beyond
Year: 2014

Transcriptional analysis of the human BPIFA1/SPLUNC1 gene
Source: Annual Congress 2013 –Stress responses and T-cell behaviour in the lung
Year: 2013

NF-κB-EGFR cross talk in lung cell proliferation
Source: International Congress 2014 – Cell biology 2014
Year: 2014

Anti-inflammatory action of Gibberellin in lung epithelial cells is mediated by modification of NF-κB related kinase expression
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014


Expression of CX3CL1 and CX3CR1 in human asthmatic lung in relation to cell survival
Source: International Congress 2014 – New mechanisms in the pathogenesis of asthma and other lung diseases
Year: 2014

Lymphocyte senescence in COPD is associated with loss of glucocorticoid receptor expression by cytotoxic/ pro-inflammatory lymphocytes
Source: International Congress 2014 – Effect of cigarette smoke on cell behaviour: cell biology, signalling and senescence
Year: 2014

Vitamin D increases anti-microbial activity in human airway epithelial cells
Source: International Congress 2014 – Mechanistic studies of the airway epithelium
Year: 2014

The role of Clara cell senescence in the pathogenesis of COPD
Source: International Congress 2014 – Effect of cigarette smoke on cell behaviour: cell biology, signalling and senescence
Year: 2014