The prevalence and severity of bronchial hyperresponsiveness (BHR) in asthmatic children in general practice
W. Hagmolen of ten Have, N. J. van den Berg, P. J. E. Bindels, J. van der Palen, W. M. C. van Aalderen (Almere, Enschede, Amsterdam, The Netherlands)
Source: Annual Congress 2002 - Asthma in primary care - Assessment and control
Session: Asthma in primary care - Assessment and control
Session type: Thematic Poster Session
Number: 591
Disease area: Airway diseases, Paediatric lung diseases
Abstract Background: The degree of BHR, in relation with the presence of symptoms, is generally accepted as an estimate of asthma severity. The majority of asthmatic children is treated in general practice. Aim of the study: To assess the prevalence and severity of BHR in children with asthma in general practice. Methods: 800 Children treated in general practice who used asthma medication in the previous year were asked to participate. BHR was evaluated in 373 of these possible asthmatic children (age:7-16) by a methacholine challenge test. The degree of bronchial responsiveness was expressed as PD20. Results: 277(74%) of all participating children were hyperresponsive according to the PD20: 55(20%) severe (PD20<0.075 mg), 101(36%) moderate (PD20 0.075-0.30mg), 63(23%) mild (PD20 0.30-1.0 mg) and 58(21%) borderline (PD20 1.0-4.0mg). In 13(3.5%) the inhalation challenge was not started because of a FEV1<75% of predicted. 72 children did not demonstrate BHR. In 11 children performance of lungfunction was technically inadequate. Conclusion: Two-fifth of children treated in general practice with asthma medication demonstrate moderate to severe BHR and sometimes even severe airflow obstruction. These data could be an indication that asthmatic children are not using appropriate medication.
Rating:
You must login to grade this presentation.
Share or cite this content
Citations should be made in the following way:
W. Hagmolen of ten Have, N. J. van den Berg, P. J. E. Bindels, J. van der Palen, W. M. C. van Aalderen (Almere, Enschede, Amsterdam, The Netherlands). The prevalence and severity of bronchial hyperresponsiveness (BHR) in asthmatic children in general practice. Eur Respir J 2002; 20: Suppl. 38, 591
You must login to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
Related content which might interest you:
Related content which might interest you:
The relationship between airways inflammation, atopy and bronchial hyper-responsiveness in young adults with mild to moderate asthma Source: Annual Congress 2010 - Clinical aspects and treatment of asthma and allergic respiratory diseases Year: 2010
Absence of association between bronchial hyperresponsiveness and current wheezing in school children in Brazil: a different phenotype of asthma? Source: Annual Congress 2006 - New features of paediatric asthma Year: 2006
Individual allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children Source: Eur Respir J 2002; 19: 288-293 Year: 2002
Are asymptomatic airway hyperresponsiveness and allergy risk factors for asthma? A longitudinal study Source: Eur Respir J 2008; 32: 70-76 Year: 2008
Relationship of atopy, asthma severity and bronchial hyperresponsiveness Source: Eur Respir J 2001; 18: Suppl. 33, 429s Year: 2001
Perception of bronchoconstriction is associated with the severity of asthma in children Source: Annual Congress 2005 - Monitoring paediatric asthma Year: 2005
Upper and lower airway inflammation and bronchial hyperresponsiveness in allergic rhinitis children with or without asthma Source: Annual Congress 2011 - Biological correlates and comorbidities of childhood asthma/allergy Year: 2011
Bronchial hyperresponsiveness and asthma severity in the EGEA study Source: Eur Respir J 2003; 22: Suppl. 45, 294s Year: 2003
Wheezing, atopy, and bronchial hyperresponsiveness in exposed and unexposed female workers Source: Annual Congress 2005 - Cleaning and cooking: a risk for occupational and household asthma Year: 2005
Bronchial hyperresponsiveness to methacholine and exercise, relation to allergy in asthma patients Source: Eur Respir J 2002; 20: Suppl. 38, 504s Year: 2002
Bronchial hyperresponsiveness and perception of dyspnea in children with allergic rhinitis and bronchial asthma Source: Eur Respir J 2004; 24: Suppl. 48, 441s Year: 2004
Socioeconomic position, lung function and bronchial responsiveness in prepubertal children Source: Annual Congress 2007 - Pets, dust and colds: early life exposures and risk of asthma Year: 2007
Sputum eosinophilia, airway hyperresponsiveness and airway narrowing in young adults with former asthma Source: Eur Respir J 2005; 26: Suppl. 49, 733s Year: 2005
The burden of airway hyperresponsiveness on the control of asthma Source: Annual Congress 2011 - Update on monitoring airway diseases Year: 2011
Relationship between bronchial hyperresponsiveness and response to β2 -agonists in steroid-naïve patients with mild asthma Source: Eur Respir J 2002; 20: Suppl. 38, 503s Year: 2002
Different associations of inflammation and current smoking with bronchial hyperresponsiveness (BHR) to histamine and BHR to AMP in families with asthma Source: Eur Respir J 2002; 20: Suppl. 38, 410s Year: 2002
The effect of obesity on the bronchial hyperresponsiveness of asthmatic children Source: Annual Congress 2013 –Asthma treatment and management in children Year: 2013
The feasibility of airways hyperresponsiveness as an inclusion criterion for studies on childhood asthma Source: Eur Respir J 2001; 17: 887-891 Year: 2001
Role of histamine bronchial hyperresponsiveness (BHR) in the diagnosis of occupational asthma (OA) to latex Source: Eur Respir J 2003; 22: Suppl. 45, 576s Year: 2003
The incidence of respiratory symptoms and sensitisation in baker apprentices Source: Eur Respir J 2008; 32: 452-459 Year: 2008