Source: Annual Congress 2002 - Asthma in primary care - Assessment and control
Disease area: Airway diseases

Abstract

On the basis of a French observational survey performed in September-November 2000, several scores of the Juniper's asthma control questionnaire (ACQ) were assessed to determine a reasonable cut-off value allowing to define asthma control. A total of 1218 patients completed the questionnaire; in parallel, asthma control was assessed by their physician with a pragmatic interiew based on three criteria: no nocturnal symptoms during the last 5 days, no exercise dyspnoea, no more than two intakes of β2-agonists during the last 7 days. Sensitivity and specificity were determined for various ACQ scores. A ROC analysis was performed, showing the best compromise between sensitivity and specificity for a cut-off point at 1.25.
Juniper score 0.25 0.50 0.75 1.00 1.25 1.50 1.75 2.00 3.00
Sensitivity 0.987 0.968 0.927 0.907 0.841 0.764 0.680 0.640 0.446
Specificity 0.274 0.574 0.761 0.803 0.908 0.932 0.966 0.979 0.997
Even if, when interviewed by their physician, controlled patients should ideally be using no β2-agonists, have no nocturnal symptoms and no exercise dyspnoea, these preliminary results offer a useful approach in the public domain for trying to decide what Juniper's ACQ score should be used for including patients in clinical trials and for adjusting asthma treatment in routine practice.

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Citations should be made in the following way:
Y. Martinat, Y. Rogeaux, K. Mezzi (Lyon, Villeneuve d'Ascq, Cergy, France). Sensitivity and specificity of the Juniper's asthma control questionnaire scores for the assessment of good vs poor asthma control: results of the J.A.C.I.N.T.E survey. Eur Respir J 2002; 20: Suppl. 38, 587

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