Closed pleural biopsy in diagnosis of pleural effusion

J. Soja, A. Szlubowski, D. Wasowski, K. Sladek (Krakow, Poland)

Source: Annual Congress 2002 - Pleural disease
Session: Pleural disease
Session type: Thematic Poster Session
Number: 535
Disease area: Respiratory infections, Thoracic oncology

Congress or journal article abstract

Abstract

The aim of the study was to assess closed pleural biopsy (CPB) as a diagnostic method of pleural effusion.
CPB is indicated for evaluation of an exudative pleural effusion. CPB using Cope needle was performed in 55 patients, proceeded by pleural ultrasound examination. It helped to obtain specimen for histopathological and microbiological examination even with cases of small amount of fluid.
In all 55 patients CPB enabled to diagnose 8 cases with neoplasmatic effusions (majority being adenocarcinomas) and 7 cases of Tuberculosis in histopathological examination. There were 40 cases with non-specific inflammatory changes. In 17 patients videothoracoscopy (VATS) was carried out and 13 of those had post-inflammatory changes. In 4 cases, however we confirmed neoplastic pleural infiltrates. In the remaining 23 patients who were followed-up for over period one year following complications were noted: 14 - post-inflammatory changes, 4-Tuberculosis, 5-neoplasms.
CPB proves to be efficient method in diagnostic of Tuberculosis and malignant pleural effusions. However, in approximately 30% of cases with post-inflammatory changes, malignancy and Tuberculosis were undiagnosed. This in turn implicates the necessity for further diagnostic procedures including VATS.


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J. Soja, A. Szlubowski, D. Wasowski, K. Sladek (Krakow, Poland). Closed pleural biopsy in diagnosis of pleural effusion. Eur Respir J 2002; 20: Suppl. 38, 535

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