e-learning
resources
Munich 2014
Sunday, 07.09.2014
ILDs 3
Login
Search all ERS
e-learning
resources
Disease Areas
Airways Diseases
Interstitial Lung Diseases
Respiratory Critical Care
Respiratory Infections
Paediatric Respiratory Diseases
Pulmonary Vascular Diseases
Sleep and Breathing Disorders
Thoracic Oncology
Events
International Congress
Courses
Webinars
Conferences
Research Seminars
Journal Clubs
Publications
Breathe
Monograph
ERJ
ERJ Open Research
ERR
European Lung White Book
Handbook Series
Guidelines
All ERS guidelines
e-learning
CME Online
Case reports
Short Videos
SpirXpert
Procedure Videos
CME tests
Reference Database of Respiratory Sounds
Radiology Image Challenge
Brief tobacco interventions
EU Projects
VALUE-Dx
ERN-LUNG
ECRAID
UNITE4TB
Disease Areas
Events
Publications
Guidelines
e-learning
EU Projects
Login
Search
Changes in PH of exhaled breath condensate after specific inhalation challenge test, in patients with hypersensitivity pneumonitis
I. Ojanguren, M. J. Cruz, A. Villar, F. Morell, X. Muñoz (Barcelona, Spain)
Source:
International Congress 2014 – ILDs 3
Session:
ILDs 3
Session type:
Thematic Poster Session
Number:
783
Disease area:
Interstitial lung diseases
Abstract
INTRODUCTION:The measurement of pH in exhaled breath condensate (EBC) has proven to be useful for monitoring pulmonary inflammation. The aim of this study was to investigate possible changes in the pH values of EBC in patients with hypersensitivity pneumonitis (NH) after specific inhalation challenge (SIC).METHODS:The study population consisted of 99 patients with suspected NH induced by exposure to avian antigens or fungi. 52 patients had a positive SIC and 47 patients had negative. EBC samples were collected before and after performing the SIC in all patients. In all samples the pH values were determined after degassing with helium. ROC curves were performed to calculate the more significant decrease of pH value to predict the positivity of SIC.RESULTS:In patients with a positive SIC, the pH of EBC post-SIC was significantly lower (median: 8.04 range: 3.91) than in patients with a negative SIC (median: 8.26 range: 2.49), (p = 0.046). The ROC curve showed that a decrease in the pH of the EBC of 0.4 after the SIC had a sensitivity of 20% (CI: 7-29%) and specificity of 83% (CI: 81-98%). In patients exposed to fungal antigens, 0.4 decrease of the pH in the EBC, showed a sensitivity of 31% (CI: 12-58%) and a specificity of 100% (CI: 77-100 %).
CONCLUSION:The pH of the EBC, in conjunction with the SIC, could be useful for the diagnosis of NH.
Rating:
You must
login
to grade this presentation.
Share or cite this content
Citations should be made in the following way:
I. Ojanguren, M. J. Cruz, A. Villar, F. Morell, X. Muñoz (Barcelona, Spain). Changes in PH of exhaled breath condensate after specific inhalation challenge test, in patients with hypersensitivity pneumonitis. Eur Respir J 2014; 44: Suppl. 58, 783
You must
login
to share this Presentation/Article on Twitter, Facebook, LinkedIn or by email.
Member's Comments
No comment yet.
You must
Login
to comment this presentation.
Related content which might interest you:
Panel discussion: ANCA associated vasculitis and lung disease
Panel discussion on genetics in pulmonary fibrosis
Impact of Dexamethasone on pathogen profile of COVID-19 patients requiring intensive care: a multicentre retrospective study
Related content which might interest you:
Prediction of CF exacerbations in children by exhaled inflammation markers
Source: International Congress 2015 – Cystic fibrosis: physiology, biomarkers, microbiology and miscellaneous
Year: 2015
Exhaled breath analysis for identifying eosinophilic and neutrophilic inflammation in a mixed population of patients with asthma or COPD
Source: International Congress 2016 – Assessing lower airway inflammation with different tools
Year: 2016
Changes in lung mechanics and gas exchange in patients with pulmonary sarcoidosis (PS)
Source: International Congress 2014 – Innovative technology and techniques in respiratory function
Year: 2014
Inflammatory markers in the exhaled breath condensate from patients with pulmonary sarcoidosis: comparison with BALF
Source: Eur Respir J 2006; 28: Suppl. 50, 353s
Year: 2006
Volatile organic compounds in exhaled breath of patients with COPD ± lung cancer and their correlation with FEV1-values
Source: International Congress 2014 – The assessment of comorbidities
Year: 2014
Relation of exhaled breath temperature and systemic markers of inflammation and remodelling in stable bronchial asthma
Source: International Congress 2016 – Airway biomarkers
Year: 2016
Treatment response in hypersensitivity pneumonitis
Source: International Congress 2016 – Orphan diseases II
Year: 2016
Correlation between lung function and exhaled breath condensate biomarkers of inflammation in pulmonary diseases
Source: Annual Congress 2009 - Lung function in adults and children
Year: 2009
Annual changes in pulmonary function are independent prognostic factors for the patients with chronic hypersensitivity pneumonia
Source: International Congress 2014 – ILDs 3
Year: 2014
Exhaled breath condensate hydrogen peroxide in obstructive airways disease
Source: International Congress 2014 – Airway biomarkers
Year: 2014
Inflammatory markers in exhaled breath condensate in bronchiectasis
Source: Eur Respir J 2004; 24: Suppl. 48, 707s
Year: 2004
Exhaled breath condensate biomarkers in COPD
Source: Eur Respir J 2008; 32: 472-486
Year: 2008
Asbestos-related disorders (ARDs): Influence of pleural plaques and pulmonary fibrosis due to asbestos exposure on lung function decline (LFD)
Source: International Congress 2014 – ILDs 5
Year: 2014
Reproducibility of exhaled breath condensate pH in chronic obstructive pulmonary disease
Source: Eur Respir J 2005; 25: 269-274
Year: 2005
Exhaled NO but not eosinophilic inflammation is reduced by inhaled corticosteroid treatment in COPD
Source: Annual Congress 2013 –Novel pharmacological findings in the management of respiratory disorders
Year: 2013
Exhaled particles from small airways in COPD patients – A pilot study
Source: International Congress 2014 – Monitoring airway diseases with lung function tests
Year: 2014
Acidity of the exhaled breath condensate in assessing bronchial challenge with exercise in children: Effect of deaeration
Source: Annual Congress 2013 –Monitoring asthma: genes, cells and molecules
Year: 2013
Myeloperoxidase in exhaled breath condensate reflects the status of lung parenchyma during the exacerbation of chronic obstructive pulmonary disease
Source: Eur Respir J 2005; 26: Suppl. 49, 54s
Year: 2005
Can Scond and Sacin be estimated from two multiple breath washout tests across childhood?
Source: International Congress 2015 – Paediatric respiratory physiology
Year: 2015
MicroRNA-26a expression in exhaled breath condensate correlates with pulmonary exacerbation in cystic fibrosis
Source: Virtual Congress 2020 – Intercellular communication in tissue remodelling of chronic lung diseases
Year: 2020
We use cookies on our website to give you the most relevant experience by remembering your preferences and repeat visits. By clicking "Accept", you consent to the use of the cookies.
Accept