Airborne endotoxin concentrations in domestic environment

A. Lintz, C. Vincent, S. Guggino (Strasbourg, France)

Source: Annual Congress 2002 - Airway obstruction measurement (FOT - NEP) sleep and lung sound analysis
Session: Airway obstruction measurement (FOT - NEP) sleep and lung sound analysis
Session type: Poster Discussion
Number: 329
Disease area: Airway diseases

Congress or journal article abstract

Abstract

Aims : To measure airborne endotoxin concentrations in domestic environment and assess the role of factors related to the house characteristics.
Material and Methods : Each dwelling characteristics (presence of plants, pets or fitted carpets, temperature and relative humidity) were recorded. Airborne individual samples (n = 223) and static samples (n = 80 in living-rooms and n = 38 in bedrooms) were carried out in 75 dwellings. Individual measurements were performed using glass fibre filters (Millipore, London) related to a portable pump (Gilair Panametrics, France) at 2 L/min for 8h, and static measurements with a pump (Bioblock, France) at 20 L/min for 1h. Endotoxin measurements were performed using the Limulus method (Chromogenix AB*, Sweden).
Results : Mean airborne endotoxin levels using individual samplers was 0.16 (+/- 0. 09) ng/m3 (n = 75 dwellings) ; and were 0.17 (+/- 0.15) ng/m3 in living-rooms and 0.19 (+/- 0.19) ng/m3 in bedrooms using static samplers. Among the studied factors, only the presence of animals caused significant increase in airborne endotoxin concentrations (i.e., mean of 0.31 ng/m3 compared to 0.11 ng/m3; p = 0.001) with static samplers.
Conclusions : Our results suggest that :
1. Levels of airborne endotoxin found in domestic environment were comparable to those found in animal facilities and dramatically lower than those in swine confinement, poultry and cotton mills.
2. Presence of animals increased airborne endotoxin levels.
This study was supported by the Ministere of the Environment.


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A. Lintz, C. Vincent, S. Guggino (Strasbourg, France). Airborne endotoxin concentrations in domestic environment. Eur Respir J 2002; 20: Suppl. 38, 329

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