Relationship between cough events duration and cough expiratory flow-time in restrictive and ostructive diseases

F. Dalmasso, E. Isnardi, L. Sudaro, R. Mantovano, A. Mazzuccato (Turin, Italy)

Source: Annual Congress 2002 - Airway obstruction measurement (FOT - NEP) sleep and lung sound analysis
Session: Airway obstruction measurement (FOT - NEP) sleep and lung sound analysis
Session type: Poster Discussion
Number: 324
Disease area: Airway diseases

Congress or journal article abstract

Abstract

Aim of this study was to compare the time duration of cough acoustic (CAD) events and expiratory flows / time of cough(CPEF; CFET) in restrictive (6 Patients-Pts-) and obstructive respiratory diseases (8Pts). All Pts were invited to give at least four big voluntary coughs before and during the forced expiratory efforts in a pneumothacograph (Lilly MasterLab, Jaeger). The cough sounds before the test where recorded in free field, (cassette corder TCS-100DV SONY) and then analysed by [dsquote]Spectra Lab-FFT Spectral analysis System[dsquote] (Poulsbo,WA) and audio card Tahiti for control. The mean values of cough events duration (CAD) before and during expiratory effort (CPEF,CFET) and VC, FEV1, FET were calculated for each patient and then the correlation coefficient of Pearson (P.c.) and Passing & Bablok comparison method were applied to all measured parameters. The maximum of correlation was found between FET and CFET ( P.c.= 0.718) and between CAD and CFET (P.c.= 0.330) in all studied patients. Good correlation was found between CAD and FEV1 when the restrictive and obstructive patients where considered separately. In COLD patients a good inverse correlation (P.c.=-0.264) was found between CAD and FEV1.
In conclusion, the time duration of a cough events (from 200 to 2.000 ms) closely correlating with the functional parameters, can help to detect the underlying chronic disease.
Therefore time duration of the cough's event can be very useful in the diagnostic screening procedures and in the studies of epidemiology. More data will make better the value of the pattern of CAD and increase the Pearson coefficient between CAD and the considered diseases.


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F. Dalmasso, E. Isnardi, L. Sudaro, R. Mantovano, A. Mazzuccato (Turin, Italy). Relationship between cough events duration and cough expiratory flow-time in restrictive and ostructive diseases. Eur Respir J 2002; 20: Suppl. 38, 324

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