Is attended polysomnography necessary for autoCPAP titration?
O. Marrone, G. Insalaco, A. Salvaggio, G. Sciortino, G. Bonsignore (Palermo, Italy)
Source: Annual Congress 2002 - Airway obstruction measurement (FOT - NEP) sleep and lung sound analysis
Disease area: Sleep and breathing disorders
Abstract The purpose of this study was to verify whether automatic continuous positive airway pressure (autoCPAP) application in an unassisted environment and without simultaneous polysomnographic monitoring allows reliable pressure titration in newly diagnosed patients with obstructive sleep apnoea syndrome (OSAS). Thirty subjects with newly diagnosed OSAS (AHI 56.4±]19,9 (SD) Epworth score 11.4±]6.9), after a short diurnal adaptation period to nasal ventilation, underwent a nocturnal polysomnography (PS-2 Compumedics, Abbotsford, Australia) during application of an autoCPAP machine (AutoSet T, ResMed, Sydney, Australia). After study initiation, a technician was allowed to intervene only if nasal mask had been pulled-off and had to be repositioned. If a CPAP level with normoxia and regular breathing was reached, CPAP titration was considered successful unless: a) sleep efficiency was <50%; b) supine sleep posture was maintained for <2 hours; c) REM sleep was absent. Two subjects requested early CPAP discontinuation. In all but one subject, who was the most obese in the sample (BMI 48.8 Kg/m2) and had bronchial asthma, an effective CPAP level was reached. Three patients pulled-off the mask, requiring technician help. In no subject titration was considered unsuccessful due to low sleep efficiency or persistent lateral decubitus, while one subject showed no REM sleep. These data indicate that, in most instances, CPAP autotitration in an unattended environment is feasible. EEG monitoring during autotitration, although rarely, may help to identify subjects who need to repeat a titration night. Some failures in titration may depend on machine ineffectiveness in patients with peculiar characteristics.
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O. Marrone, G. Insalaco, A. Salvaggio, G. Sciortino, G. Bonsignore (Palermo, Italy). Is attended polysomnography necessary for autoCPAP titration?. Eur Respir J 2002; 20: Suppl. 38, 320
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